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NCT03972202 · ClinicalTrials.gov registry record · NA
The Role of Cerebellum in Speech
A NA study of Healthy and Dysarthria, sponsored by University of California, San Francisco.
- Active
- Registry status
- NA
- Development phase
- 660
- Enrollment target
- 3
- Study locations
NCT03972202: Active NA study of Healthy and Dysarthria, sponsored by University of California, San Francisco.
NCT03972202 is a NA study of Healthy and Dysarthria that is active but no longer recruiting, run by University of California, San Francisco. The registered enrollment target is 660 participants, roughly in line with the 647-participant average among 1,090 other Healthy trials with a reported enrollment target. The trial reports 3 study locations across 2 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03972202, a NA study of Healthy and Dysarthria, is active but no longer recruiting, sponsored by University of California, San Francisco.
- ACTIVE NOT RECRUITING
- Registry status
- NA
- Development phase
- 660 participants
- Enrollment target
- 3
- Study locations
Study Summary
This study will investigate the how the cerebellum is involved in speech motor learning over time and short-term corrections in patients with cerebellar ataxia and healthy controls. This will be accomplished through three approaches: behavioral studies, magnetic resonance imaging (MRI), and transcranial magnetic stimulation (TMS). During behavioral studies, participants will be asked to speak into a microphone while their voice is played back over earphones, and to do other speaking tasks. MRI will be acquired to perform a detailed analysis on brain function and anatomy related to speech and the cerebellum. In healthy controls, TMS will also be performed to temporarily disrupt the cerebellum before, during, or after the participant performs speaking tasks. Patients with cerebellar ataxia and healthy volunteers will be asked to complete behavioral studies and/or MRI; healthy volunteers may be asked to additionally participate in TMS.
Primary Outcome
Percent compensation is calculated as the following ratio: -100\*(change in acoustic feature produced by the subject)/(change in acoustic feature caused by auditory feedback alteration). The negative sign ensures that changes produced by the subject that oppose the auditory feedback alteration changes are counted as positive compensation. Acoustic features used to compute percent compensation depend on the experiment performed and will include pitch or formant frequencies of subjects' output spe
Conditions Studied
Interventions
- DEVICE TMS
- DIAGNOSTIC_TEST MRI
- BEHAVIORAL Speech-motor behavioral testing
Study Locations (3)
California
- University of California, Berkeley - Berkeley
- University of California, San Francisco - San Francisco
Wisconsin
- University of Wisconsin--Madison - Madison
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 660 participants |
| Start Date | 2019-09-15 |
| Est. Completion | 2030-05-31 |
| Phase | NA |
What the registry record for NCT03972202 still lists
NCT03972202 is an interventional study that assigns participants to a tested intervention. The registered 660 participants enrollment target is mid-sized for trials with a published cap, roughly in line with the 647-participant average among 1,090 other Healthy trials with a reported enrollment target.
The record links to 3 conditions, with Healthy appearing as the primary indexed condition, and to 3 interventions - of which TMS is the first listed.
NCT03972202 reports a single indexed study location in California, Wisconsin.
Frequently Asked Questions
What is clinical trial NCT03972202 about?
NCT03972202 is a clinical study titled "The Role of Cerebellum in Speech". This study will investigate the how the cerebellum is involved in speech motor learning over time and short-term corrections in patients with cerebellar ataxia and healthy controls. This will be accomplished through three approaches: behavioral studies, magnetic resonance imaging (MRI), and transcra...
What is the current status of trial NCT03972202?
This trial is currently active not recruiting. It is a NA study. The enrollment target is 660 participants. The study started on 2019-09-15. Estimated completion is 2030-05-31.
What conditions does trial NCT03972202 study?
This clinical trial studies the following conditions: Healthy, Dysarthria, Cerebellar Ataxia.
What interventions are being tested in trial NCT03972202?
The interventions under investigation include: TMS (DEVICE), MRI (DIAGNOSTIC_TEST), Speech-motor behavioral testing (BEHAVIORAL).
Who is sponsoring clinical trial NCT03972202?
This trial is sponsored by University of California, San Francisco, which has 1,713 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT03972202 being conducted?
This trial has 3 study locations across California, Wisconsin. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Healthy
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT03972202's enrollment target sits among peer trials
660 39th of 1090 higher than 1,052 of 1,090 other Healthy trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Healthy trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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