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NCT03971474 · ClinicalTrials.gov registry record · Phase 2

Ramucirumab and Pembrolizumab Versus Standard of Care in Treating Patients With Stage IV or Recurrent Non-small Cell Lung Cancer (A Lung-MAP Non-Match Treatment Trial)

A Phase 2 study, sponsored by SWOG Cancer Research Network.

Completed
Registry status
Phase 2
Development phase
166
Enrollment target

NCT03971474 is a Phase 2 study that has completed, run by SWOG Cancer Research Network. The registered enrollment target is 166 participants.

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The verdict

NCT03971474, a Phase 2 study, has completed, sponsored by SWOG Cancer Research Network.

COMPLETED
Registry status
Phase 2
Development phase
166 participants
Enrollment target

Study Summary

This phase II Lung-MAP non-Match treatment trial studies how well ramucirumab and pembrolizumab work versus standard of care in treating patients with non-small cell lung cancer that is stage IV or has come back. Immunotherapy with monoclonal antibodies, such as ramucirumab and pembrolizumab, may help the body's immune system attack the cancer, and may interfere with the ability of tumor cells to grow and spread. Drugs used in standard of care chemotherapy for non-small cell lung cancer, such as docetaxel, gemcitabine hydrochloride, and pemetrexed, work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Giving ramucirumab and pembrolizumab together may work better in treating patients with non-small lung cancer compared to standard of care.

Interventions

  • BIOLOGICAL Pembrolizumab
  • DRUG Docetaxel
  • DRUG Pemetrexed
  • DRUG Gemcitabine
  • DRUG Gemcitabine Hydrochloride

Trial Details

FieldValue
Enrollment Target 166 participants
Start Date 2019-05-28
Est. Completion 2024-01-01
Phase Phase 2

Sponsor

SWOG Cancer Research Network

270 total trials

What the Registry Record Tells You About NCT03971474

The ClinicalTrials.gov registry entry for NCT03971474 describes a study currently listed as completed, categorized as Phase 2. The registered enrollment target is 166 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is SWOG Cancer Research Network, which has 270 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 5 interventions - of which Pembrolizumab is the first listed.

NCT03971474 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT03971474 about?

NCT03971474 is a clinical study titled "Ramucirumab and Pembrolizumab Versus Standard of Care in Treating Patients With Stage IV or Recurrent Non-small Cell Lung Cancer (A Lung-MAP Non-Match Treatment Trial)". This phase II Lung-MAP non-Match treatment trial studies how well ramucirumab and pembrolizumab work versus standard of care in treating patients with non-small cell lung cancer that is stage IV or has come back. Immunotherapy with monoclonal antibodies, such as ramucirumab and pembrolizumab, may he...

What is the current status of trial NCT03971474?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 166 participants. The study started on 2019-05-28. Estimated completion is 2024-01-01.

What interventions are being tested in trial NCT03971474?

The interventions under investigation include: Pembrolizumab (BIOLOGICAL), Docetaxel (DRUG), Pemetrexed (DRUG), Gemcitabine (DRUG), Gemcitabine Hydrochloride (DRUG).

Who is sponsoring clinical trial NCT03971474?

This trial is sponsored by SWOG Cancer Research Network, which has 270 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.