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NCT03968848 · ClinicalTrials.gov registry record · Phase 1
Investigate the Influence of Severe Hepatic Impairment on the Pharmacokinetics of Acalabrutinib and Its Metabolite
A Phase 1 study, sponsored by Acerta Pharma.
- Completed
- Registry status
- Phase 1
- Development phase
- 16
- Enrollment target
NCT03968848: Completed Phase 1 study, sponsored by Acerta Pharma.
NCT03968848 is a Phase 1 study that has completed, run by Acerta Pharma. The registered enrollment target is 16 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (73% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03968848, a Phase 1 study, has completed, sponsored by Acerta Pharma.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 16 participants
- Enrollment target
Study Summary
This study is investigate the influence of severe hepatic impairment on the pharmacokinetics of acalabrutinib and its metabolite.
Primary Outcome
Area Under the Concentration-Time Curve
Interventions
- DRUG acalabrutinib
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 16 participants |
| Start Date | 2018-11-12 |
| Est. Completion | 2019-03-29 |
| Phase | Phase 1 |
What the finished NCT03968848 record still lists
NCT03968848 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 16 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (73% lower).
The record links to 0 conditions, and to 1 intervention - of which acalabrutinib is the first listed.
NCT03968848 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT03968848 about?
NCT03968848 is a clinical study titled "Investigate the Influence of Severe Hepatic Impairment on the Pharmacokinetics of Acalabrutinib and Its Metabolite". This study is investigate the influence of severe hepatic impairment on the pharmacokinetics of acalabrutinib and its metabolite.
What is the current status of trial NCT03968848?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 16 participants. The study started on 2018-11-12. Estimated completion is 2019-03-29.
What interventions are being tested in trial NCT03968848?
The interventions under investigation include: acalabrutinib (DRUG).
Who is sponsoring clinical trial NCT03968848?
This trial is sponsored by Acerta Pharma, which has 38 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT03968848's enrollment target sits among peer trials
16 1786th of 2000 higher than 203 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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