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NCT03962894 · ClinicalTrials.gov registry record · Phase 4
Early Administration of Steroids in the Ambulance Setting
A Phase 4 study, sponsored by University of Florida.
- Completed
- Registry status
- Phase 4
- Development phase
- 834
- Enrollment target
NCT03962894: Completed Phase 4 study, sponsored by University of Florida.
NCT03962894 is a Phase 4 study that has completed, run by University of Florida. The registered enrollment target is 834 participants, above the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (61% higher). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03962894, a Phase 4 study, has completed, sponsored by University of Florida.
- COMPLETED
- Registry status
- Phase 4
- Development phase
- 834 participants
- Enrollment target
Study Summary
Asthma is the most common chronic disease of childhood and is a leading cause of emergency medical treatment. For children experiencing an asthma exacerbation, emergency department (ED) guidelines recommend early systemic corticosteroid (CS) administration, since studies have shown associated, time-sensitive, decreases in hospital admissions and ED length-of-stay (LOS). For patients who are treated by 911 emergency medical services (EMS) first, there exists an opportunity for even earlier administration of CS, prior to ED arrival. Yet, preliminary data demonstrate that currently less than 10% of EMS pediatric asthma patients receive CS prior to ED arrival. Given the known time-sensitivity of CS' effects on patient outcomes, the investigators hypothesize that even earlier EMS administration of CS will decrease hospital admissions, ED LOS, and intensive care unit admissions for pediatric patients with an acute asthma exacerbation. Using a pragmatic observation design in multiple EMS agencies, we will enroll patients to analyze clinical outcomes and comparative costs of EMS CS administration, and how both are influenced by EMS transport time. That novel combination of analyses will help build evidence-based guidelines adaptable for diverse EMS agencies nationwide.
Primary Outcome
Number of admissions to an inpatient unit (general or ICU) for an asthma exacerbation
Interventions
- DRUG Prednisolone
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 834 participants |
| Start Date | 2019-04-01 |
| Est. Completion | 2024-12-31 |
| Phase | Phase 4 |
What the finished NCT03962894 record still lists
NCT03962894 is an interventional study that assigns participants to a tested intervention. The registered 834 participants enrollment target is mid-sized for trials with a published cap, above the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (61% higher).
The record links to 0 conditions, and to 1 intervention - of which Prednisolone is the first listed.
NCT03962894 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT03962894 about?
NCT03962894 is a clinical study titled "Early Administration of Steroids in the Ambulance Setting". Asthma is the most common chronic disease of childhood and is a leading cause of emergency medical treatment. For children experiencing an asthma exacerbation, emergency department (ED) guidelines recommend early systemic corticosteroid (CS) administration, since studies have shown associated, time-...
What is the current status of trial NCT03962894?
This trial is currently completed. It is a Phase 4 study. The enrollment target is 834 participants. The study started on 2019-04-01. Estimated completion is 2024-12-31.
What interventions are being tested in trial NCT03962894?
The interventions under investigation include: Prednisolone (DRUG).
Who is sponsoring clinical trial NCT03962894?
This trial is sponsored by University of Florida, which has 1,106 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT03962894's enrollment target sits among peer trials
834 92nd of 2000 higher than 1,909 of 2,000 other Phase 4 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 4 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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