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NCT03957954 · ClinicalTrials.gov registry record · Phase 1

Stem Cell Therapy for Limbal Stem Cell Deficiency

A Phase 1 study of Limbal Stem Cell Deficiency, sponsored by University of California, Los Angeles.

Active
Registry status
Phase 1
Development phase
20
Enrollment target
1
Study location

NCT03957954 is a Phase 1 study of Limbal Stem Cell Deficiency that is active but no longer recruiting, run by University of California, Los Angeles. The registered enrollment target is 20 participants. The trial reports 1 study location across 1 state.

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The verdict

NCT03957954, a Phase 1 study of Limbal Stem Cell Deficiency, is active but no longer recruiting, sponsored by University of California, Los Angeles.

ACTIVE NOT RECRUITING
Registry status
Phase 1
Development phase
20 participants
Enrollment target
1
Study location

Study Summary

This phase I study will collect preliminary information on the activity and safety of cLSC. We will investigate the ability to manufacture and transplant cLSC onto the cornea successfully at the time of surgery (feasibility), and have cLSC begin to populate the ocular surface (efficacy) without serious adverse events (safety).

Interventions

  • BIOLOGICAL cLSC
  • DEVICE Scleral contact lens (SCL)

Study Locations (1)

California

  • University of California - Los Angeles

Trial Details

FieldValue
Enrollment Target 20 participants
Start Date 2020-09-30
Est. Completion 2027-04-30
Phase Phase 1

What the Registry Record Tells You About NCT03957954

The ClinicalTrials.gov registry entry for NCT03957954 describes a study currently listed as active not recruiting, categorized as Phase 1. The registered enrollment target is 20 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of California, Los Angeles, which has 897 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Limbal Stem Cell Deficiency appearing as the primary indexed condition, and to 2 interventions - of which cLSC is the first listed.

NCT03957954 reports 1 study location spanning 1 distinct geographic area - top geographies include California.

Frequently Asked Questions

What is clinical trial NCT03957954 about?

NCT03957954 is a clinical study titled "Stem Cell Therapy for Limbal Stem Cell Deficiency". This phase I study will collect preliminary information on the activity and safety of cLSC. We will investigate the ability to manufacture and transplant cLSC onto the cornea successfully at the time of surgery (feasibility), and have cLSC begin to populate the ocular surface (efficacy) without seri...

What is the current status of trial NCT03957954?

This trial is currently active not recruiting. It is a Phase 1 study. The enrollment target is 20 participants. The study started on 2020-09-30. Estimated completion is 2027-04-30.

What conditions does trial NCT03957954 study?

This clinical trial studies the following conditions: Limbal Stem Cell Deficiency.

What interventions are being tested in trial NCT03957954?

The interventions under investigation include: cLSC (BIOLOGICAL), Scleral contact lens (SCL) (DEVICE).

Who is sponsoring clinical trial NCT03957954?

This trial is sponsored by University of California, Los Angeles, which has 897 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT03957954 being conducted?

This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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