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NCT03955874 · ClinicalTrials.gov registry record
Mechanical Ventilation Discontinuation Practices
A clinical trial, sponsored by Unity Health Toronto.
- Completed
- Registry status
- 1,868
- Enrollment target
NCT03955874: Completed study, sponsored by Unity Health Toronto.
NCT03955874 is a clinical trial that has completed, run by Unity Health Toronto. The registered enrollment target is 1,868 participants. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03955874 has completed, sponsored by Unity Health Toronto.
- COMPLETED
- Registry status
- 1,868 participants
- Enrollment target
Study Summary
Background: The requirement for ventilator support is a defining feature of critical illness. Weaning is the process during which the work of breathing is transferred from the ventilator back to the patient. Approximately 40% of the total time spent on ventilators is dedicated to weaning. The extent of practice variation in how this complex and expensive technology is discontinued from critically ill patients is unknown. Meanwhile, practice variation has been shown to adversely impact upon patient safety and clinical outcomes. Purpose: To characterize practice pattern variation in weaning and the consequences of weaning variation by implementing an international, prospective observational study in Canada, the United States, the United Kingdom, Europe, India and Australia/New Zealand. Primary Objectives: To describe 1. weaning practice variation among regions in 5 domains (the use of daily screening, preferred methods of support used before initial discontinuation attempts, use of written protocols, preferred methods of evaluating spontaneous breathing, and sedation and mobilization practices). 2. the assocation between selected discontinuation strategies and important clinical outcomes (length of stay, mortality, duration of ventilation). Methods: The investigators propose to conduct a large scale, observational study involving critically ill adults requiring ventilator support for at least 24 hours to evaluate practices in discontinuing ventilators in 150 centres. The investigators will classify each new admission over the observation period according to the initial strategy that precipitated or facilitated ventilator discontinuation. Relevance: This novel study will build collaborations with critical care investigators from around the world and industry
Primary Outcome
Use of once daily screening in clinical practice
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 1,868 participants |
| Start Date | 2013-11-04 |
| Est. Completion | 2016-12-17 |
What the finished NCT03955874 record still lists
NCT03955874 is an observational study that tracks outcomes without assigning an intervention. Its 1,868 participants enrollment target places it among the larger protocols in the corpus.
The record links to 0 conditions, and to 0 interventions.
NCT03955874 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT03955874 about?
NCT03955874 is a clinical study titled "Mechanical Ventilation Discontinuation Practices". Background: The requirement for ventilator support is a defining feature of critical illness. Weaning is the process during which the work of breathing is transferred from the ventilator back to the patient. Approximately 40% of the total time spent on ventilators is dedicated to weaning. The extent...
What is the current status of trial NCT03955874?
This trial is currently completed. The enrollment target is 1,868 participants. The study started on 2013-11-04. Estimated completion is 2016-12-17.
Who is sponsoring clinical trial NCT03955874?
This trial is sponsored by Unity Health Toronto, which has 12 total clinical trials registered on ClinicalTrials.gov.
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