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NCT03954886 · ClinicalTrials.gov registry record · NA
Defocus Induced Changes on Choroidal Thickness
A NA study of Induced Defocus to the Retina, sponsored by University of Houston.
- Completed
- Registry status
- NA
- Development phase
- 48
- Enrollment target
- 1
- Study location
NCT03954886: Completed NA study of Induced Defocus to the Retina, sponsored by University of Houston.
NCT03954886 is a NA study of Induced Defocus to the Retina that has completed, run by University of Houston. The registered enrollment target is 48 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (97% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03954886, a NA study of Induced Defocus to the Retina, has completed, sponsored by University of Houston.
- COMPLETED
- Registry status
- NA
- Development phase
- 48 participants
- Enrollment target
- 1
- Study location
Study Summary
The goals of this study are to assess the short-term (10-60 minutes) effects of different magnitudes of myopic and hyperopic optical defocus on the transient thickness of the choroid in children and adults, as well as to assess the recovery period. Choroidal thickness will be measured non-invasively following 10-60 minutes of monocular exposure to -5 diopters to +5 diopters of optical defocus induced by spectacle lenses. The hypothesis is that choroidal thickness will increase with increasing myopic defocus and decrease with increasing hyperopic defocus. The relationship between the magnitude of defocus and the magnitude and direction of choroidal thickness change will be assessed.
Primary Outcome
Changes in choroidal thickness following induced myopic defocus
Conditions Studied
Interventions
- DEVICE Plus powered optical lens
Study Locations (1)
Texas
- University of Houston College of Optometry - Houston
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 48 participants |
| Start Date | 2018-05-15 |
| Est. Completion | 2021-12-31 |
| Phase | NA |
What the finished NCT03954886 record still lists
NCT03954886 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 48 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (97% lower).
The record links to 1 condition, with Induced Defocus to the Retina appearing as the primary indexed condition, and to 1 intervention - of which Plus powered optical lens is the first listed.
NCT03954886 reports a single indexed study location in Texas.
Frequently Asked Questions
What is clinical trial NCT03954886 about?
NCT03954886 is a clinical study titled "Defocus Induced Changes on Choroidal Thickness". The goals of this study are to assess the short-term (10-60 minutes) effects of different magnitudes of myopic and hyperopic optical defocus on the transient thickness of the choroid in children and adults, as well as to assess the recovery period. Choroidal thickness will be measured non-invasively...
What is the current status of trial NCT03954886?
This trial is currently completed. It is a NA study. The enrollment target is 48 participants. The study started on 2018-05-15. Estimated completion is 2021-12-31.
What conditions does trial NCT03954886 study?
This clinical trial studies the following conditions: Induced Defocus to the Retina.
What interventions are being tested in trial NCT03954886?
The interventions under investigation include: Plus powered optical lens (DEVICE).
Who is sponsoring clinical trial NCT03954886?
This trial is sponsored by University of Houston, which has 64 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT03954886 being conducted?
This trial has 1 study location across Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT03954886's enrollment target sits among peer trials
48 1381st of 2000 higher than 601 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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