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NCT03953703 · ClinicalTrials.gov registry record · Phase 2
Levocarnitine for Dry Eye in Sjogren's Syndrome
A Phase 2 study, sponsored by Vanderbilt University Medical Center.
- Completed
- Registry status
- Phase 2
- Development phase
- 15
- Enrollment target
NCT03953703: Completed Phase 2 study, sponsored by Vanderbilt University Medical Center.
NCT03953703 is a Phase 2 study that has completed, run by Vanderbilt University Medical Center. The registered enrollment target is 15 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (89% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03953703, a Phase 2 study, has completed, sponsored by Vanderbilt University Medical Center.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 15 participants
- Enrollment target
Study Summary
This study evaluates the effectiveness of levocarnitine in the treatment of dry eye in adults with Sjogren's syndrome. This will be a crossover study design with all participants receiving both levocarnitine and placebo.
Primary Outcome
Levels of inflammatory cytokines IFN-gamma, TNF-alpha, IL-17, IL-6 and IL-1beta will be measured by flow cytometric multiplexed bead assay.
Interventions
- DRUG Placebo
- DRUG Levocarnitine
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 15 participants |
| Start Date | 2021-11-17 |
| Est. Completion | 2025-09-19 |
| Phase | Phase 2 |
What the finished NCT03953703 record still lists
NCT03953703 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 15 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (89% lower).
The record links to 0 conditions, and to 2 interventions - of which Placebo is the first listed.
NCT03953703 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT03953703 about?
NCT03953703 is a clinical study titled "Levocarnitine for Dry Eye in Sjogren's Syndrome". This study evaluates the effectiveness of levocarnitine in the treatment of dry eye in adults with Sjogren's syndrome. This will be a crossover study design with all participants receiving both levocarnitine and placebo.
What is the current status of trial NCT03953703?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 15 participants. The study started on 2021-11-17. Estimated completion is 2025-09-19.
What interventions are being tested in trial NCT03953703?
The interventions under investigation include: Placebo (DRUG), Levocarnitine (DRUG).
Who is sponsoring clinical trial NCT03953703?
This trial is sponsored by Vanderbilt University Medical Center, which has 677 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT03953703's enrollment target sits among peer trials
15 1919th of 2000 higher than 60 of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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