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NCT03946800 · ClinicalTrials.gov registry record · Phase 1
A Study of MEDI1191 in Sequential and Concurrent Combination With Durvalumab in Subjects With Advanced Solid Tumors
A Phase 1 study, sponsored by MedImmune.
- Completed
- Registry status
- Phase 1
- Development phase
- 61
- Enrollment target
NCT03946800: Completed Phase 1 study, sponsored by MedImmune.
NCT03946800 is a Phase 1 study that has completed, run by MedImmune. The registered enrollment target is 61 participants, roughly in line with the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03946800, a Phase 1 study, has completed, sponsored by MedImmune.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 61 participants
- Enrollment target
Study Summary
To evaluate MEDI1191 administered intratumorally in sequential and concurrent combination with intravenous durvalumab in patients with solid tumors.
Primary Outcome
The occurrence of DLTs will be used to establish the maximum tolerated dose (MTD) of MEDI1191.
Interventions
- BIOLOGICAL Durvalumab
- BIOLOGICAL MEDI1191
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 61 participants |
| Start Date | 2019-05-08 |
| Est. Completion | 2023-08-24 |
| Phase | Phase 1 |
What the finished NCT03946800 record still lists
NCT03946800 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 61 participants, a relatively small participant target, roughly in line with the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target.
The record links to 0 conditions, and to 2 interventions - of which Durvalumab is the first listed.
NCT03946800 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT03946800 about?
NCT03946800 is a clinical study titled "A Study of MEDI1191 in Sequential and Concurrent Combination With Durvalumab in Subjects With Advanced Solid Tumors". To evaluate MEDI1191 administered intratumorally in sequential and concurrent combination with intravenous durvalumab in patients with solid tumors.
What is the current status of trial NCT03946800?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 61 participants. The study started on 2019-05-08. Estimated completion is 2023-08-24.
What interventions are being tested in trial NCT03946800?
The interventions under investigation include: Durvalumab (BIOLOGICAL), MEDI1191 (BIOLOGICAL).
Who is sponsoring clinical trial NCT03946800?
This trial is sponsored by MedImmune, which has 210 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT03946800's enrollment target sits among peer trials
61 828th of 2000 higher than 1,170 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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