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NCT03933865 · ClinicalTrials.gov registry record · Phase 1
Acute Pain Management in Patients on Opioid Replacement Therapy
A Phase 1 study, sponsored by University of California, San Francisco.
- Terminated
- Registry status
- Phase 1
- Development phase
- 1
- Enrollment target
NCT03933865: Clinical Trial Phase 1 study, sponsored by University of California, San Francisco.
NCT03933865 is a Phase 1 study that was terminated before completion, run by University of California, San Francisco. The registered enrollment target is 1 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (98% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03933865, a Phase 1 study, was terminated before completion, sponsored by University of California, San Francisco.
- TERMINATED
- Registry status
- Phase 1
- Development phase
- 1 participants
- Enrollment target
Study Summary
This is an outpatient randomized within subject placebo-controlled human laboratory investigation of analgesia (as assessed with quantitative sensory testing; QST) from ketamine alone and in combination with hydromorphone in buprenorphine maintained participants. The goals of this project are to characterize the analgesic, subjective, and physiologic effects of ketamine combined with hydromorphone in patients on buprenorphine maintenance for opioid use disorder.
Primary Outcome
The amount of time (seconds) a participant can keep hand in cold water bath before pain becomes unbearable. The change will be the highest value after study medications have been administered subtracted from the session baseline.
Interventions
- DRUG Ketamine
- DRUG Placebos
- DRUG HYDROmorphone Injectable Solution
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 1 participants |
| Start Date | 2018-10-31 |
| Est. Completion | 2022-02-24 |
| Phase | Phase 1 |
Why NCT03933865 stopped before completion
NCT03933865 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 1 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (98% lower).
The record links to 0 conditions, and to 3 interventions - of which Ketamine is the first listed.
NCT03933865 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT03933865 about?
NCT03933865 is a clinical study titled "Acute Pain Management in Patients on Opioid Replacement Therapy". This is an outpatient randomized within subject placebo-controlled human laboratory investigation of analgesia (as assessed with quantitative sensory testing; QST) from ketamine alone and in combination with hydromorphone in buprenorphine maintained participants. The goals of this project are to cha...
What is the current status of trial NCT03933865?
This trial is currently terminated. It is a Phase 1 study. The enrollment target is 1 participants. The study started on 2018-10-31. Estimated completion is 2022-02-24.
What interventions are being tested in trial NCT03933865?
The interventions under investigation include: Ketamine (DRUG), Placebos (DRUG), HYDROmorphone Injectable Solution (DRUG).
Who is sponsoring clinical trial NCT03933865?
This trial is sponsored by University of California, San Francisco, which has 1,713 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT03933865's enrollment target sits among peer trials
1 2001st of 2000 the lowest of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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