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NCT03921658 · ClinicalTrials.gov registry record
The Role of Cytomegalovirus and Inflammation on Patient Symptoms and Outcomes in Ovarian Cancer
A clinical trial, sponsored by University of Minnesota.
- Completed
- Registry status
- 255
- Enrollment target
NCT03921658: Completed study, sponsored by University of Minnesota.
NCT03921658 is a clinical trial that has completed, run by University of Minnesota. The registered enrollment target is 255 participants. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03921658 has completed, sponsored by University of Minnesota.
- COMPLETED
- Registry status
- 255 participants
- Enrollment target
Study Summary
Cytomegalovirus (CMV), a widely prevalent virus in the general US population, has been shown to be associated with increased inflammation and mortality. Previous small pilot studies have demonstrated that latent CMV may be reactivated during chemotherapy in cancer patients, and may be associated with unfavorable cancer outcomes such as fatigue and increased mortality. The central research idea for this study, supported by previous preliminary data, is that CMV reactivation is an unrecognized complicating factor in the treatment of ovarian cancer that impacts patient outcomes. The overarching goals of this observational study are: * To assess how CMV infection is associated with ovarian cancer symptoms over the course of the disease and its treatment. * To describe the relationship between CMV reactivation in ovarian cancer patients, survival, fatigue, and other QOL outcomes, both cross-sectionally and longitudinally.
Primary Outcome
Cancer-related fatigue will be measured using the Fatigue Symptom Inventory. The scale is composed of 14 items (one is not scored). A total Disruption Index is calculated by summing items 5-11 (each item ranges from 0-10). A lower score indicates lower fatigue. Possible range is 0-70.
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 255 participants |
| Start Date | 2019-10-22 |
| Est. Completion | 2024-04-02 |
What the finished NCT03921658 record still lists
NCT03921658 is an observational study that tracks outcomes without assigning an intervention. The registered 255 participants enrollment target is mid-sized for trials with a published cap.
The record links to 0 conditions, and to 0 interventions.
NCT03921658 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT03921658 about?
NCT03921658 is a clinical study titled "The Role of Cytomegalovirus and Inflammation on Patient Symptoms and Outcomes in Ovarian Cancer". Cytomegalovirus (CMV), a widely prevalent virus in the general US population, has been shown to be associated with increased inflammation and mortality. Previous small pilot studies have demonstrated that latent CMV may be reactivated during chemotherapy in cancer patients, and may be associated wit...
What is the current status of trial NCT03921658?
This trial is currently completed. The enrollment target is 255 participants. The study started on 2019-10-22. Estimated completion is 2024-04-02.
Who is sponsoring clinical trial NCT03921658?
This trial is sponsored by University of Minnesota, which has 966 total clinical trials registered on ClinicalTrials.gov.
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