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NCT03921151 · ClinicalTrials.gov registry record · Phase 1
5HT2CR Balance in Brain Connectivity in Cocaine Dependence
A Phase 1 study, sponsored by Virginia Commonwealth University.
- Completed
- Registry status
- Phase 1
- Development phase
- 90
- Enrollment target
NCT03921151: Completed Phase 1 study, sponsored by Virginia Commonwealth University.
NCT03921151 is a Phase 1 study that has completed, run by Virginia Commonwealth University. The registered enrollment target is 90 participants, above the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (50% higher). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03921151, a Phase 1 study, has completed, sponsored by Virginia Commonwealth University.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 90 participants
- Enrollment target
Study Summary
This project will evaluate the role of the 5-HT2CR:5-HT2AR balance in impulsive action and cue reactivity in cocaine-dependent subjects as compared to non-drug using controls.
Primary Outcome
Change in fMRI activation during Go/NoGo (impulsivity) task with placebo dose vs Mirtazapine dose. Brain activation measured using blood-oxygen-level dependent (BOLD) contrast
Interventions
- DRUG Mirtazapine 15 MG Oral Tablet
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 90 participants |
| Start Date | 2014-05-13 |
| Est. Completion | 2019-01-24 |
| Phase | Phase 1 |
What the finished NCT03921151 record still lists
NCT03921151 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 90 participants, a relatively small participant target, above the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (50% higher).
The record links to 0 conditions, and to 1 intervention - of which Mirtazapine 15 MG Oral Tablet is the first listed.
NCT03921151 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT03921151 about?
NCT03921151 is a clinical study titled "5HT2CR Balance in Brain Connectivity in Cocaine Dependence". This project will evaluate the role of the 5-HT2CR:5-HT2AR balance in impulsive action and cue reactivity in cocaine-dependent subjects as compared to non-drug using controls.
What is the current status of trial NCT03921151?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 90 participants. The study started on 2014-05-13. Estimated completion is 2019-01-24.
What interventions are being tested in trial NCT03921151?
The interventions under investigation include: Mirtazapine 15 MG Oral Tablet (DRUG).
Who is sponsoring clinical trial NCT03921151?
This trial is sponsored by Virginia Commonwealth University, which has 558 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT03921151's enrollment target sits among peer trials
90 628th of 2000 higher than 1,352 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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