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NCT03920852 · ClinicalTrials.gov registry record · Phase 1
A Maximum Use Trial of Ruxolitinib Cream in Adolescent and Adult Participants With Atopic Dermatitis
A Phase 1 study, sponsored by Incyte Corporation.
- Completed
- Registry status
- Phase 1
- Development phase
- 41
- Enrollment target
NCT03920852: Completed Phase 1 study, sponsored by Incyte Corporation.
NCT03920852 is a Phase 1 study that has completed, run by Incyte Corporation. The registered enrollment target is 41 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (32% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03920852, a Phase 1 study, has completed, sponsored by Incyte Corporation.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 41 participants
- Enrollment target
Study Summary
This is an open-label maximum use trial to evaluate ruxolitinib safety and blood levels after its topical application twice daily to affected areas (≥ 25% BSA) in adolescent and adult participants with atopic dermatitis (AD) and to determine if its systemic bioavailability results in any adverse events.
Primary Outcome
Defined as any adverse event either reported for the first time or worsening of a pre-existing event after first application of study drug.
Interventions
- DRUG Ruxolitinib cream
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 41 participants |
| Start Date | 2019-05-30 |
| Est. Completion | 2019-12-26 |
| Phase | Phase 1 |
What the finished NCT03920852 record still lists
NCT03920852 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 41 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (32% lower).
The record links to 0 conditions, and to 1 intervention - of which Ruxolitinib cream is the first listed.
NCT03920852 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT03920852 about?
NCT03920852 is a clinical study titled "A Maximum Use Trial of Ruxolitinib Cream in Adolescent and Adult Participants With Atopic Dermatitis". This is an open-label maximum use trial to evaluate ruxolitinib safety and blood levels after its topical application twice daily to affected areas (≥ 25% BSA) in adolescent and adult participants with atopic dermatitis (AD) and to determine if its systemic bioavailability results in any adverse eve...
What is the current status of trial NCT03920852?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 41 participants. The study started on 2019-05-30. Estimated completion is 2019-12-26.
What interventions are being tested in trial NCT03920852?
The interventions under investigation include: Ruxolitinib cream (DRUG).
Who is sponsoring clinical trial NCT03920852?
This trial is sponsored by Incyte Corporation, which has 239 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT03920852's enrollment target sits among peer trials
41 1125th of 2000 higher than 871 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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