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NCT03917823 · ClinicalTrials.gov registry record · NA
Intercostal Cryoneurolysis Following Traumatic Rib Fractures
A NA study, sponsored by University of California, San Diego.
- Terminated
- Registry status
- NA
- Development phase
- 4
- Enrollment target
NCT03917823: Clinical Trial NA study, sponsored by University of California, San Diego.
NCT03917823 is a NA study that was terminated before completion, run by University of California, San Diego. The registered enrollment target is 4 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (100% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03917823, a NA study, was terminated before completion, sponsored by University of California, San Diego.
- TERMINATED
- Registry status
- NA
- Development phase
- 4 participants
- Enrollment target
Study Summary
Rib fractures are one of the most common injuries in trauma patients. These fractures are associated with significant pain as well as decreased ability to inspire deeply or cough to clear secretions, which together lead to pulmonary complications and a high degree of morbidity and mortality. Peripheral nerve blocks as well as epidural blocks have been used with success to improve pain control in rib fracture patients and have been associated with decreased pulmonary complications and improved outcomes. However, a single-injection nerve block lasts less than 24 hours; and, even a continuous nerve block is generally limited to 3-4 days. The pain from rib fractures usually persists for multiple weeks or months. In contrast to local anesthetic-induced nerve blocks, a prolonged block lasting a few weeks/months may be provided by freezing the nerve using a process called "cryoneurolysis". The goal of this randomized, double-masked, sham-controlled study is to evaluate the potential of cryoanalgesia to decrease pain and improve pulmonary mechanics in patients with rib fractures.
Primary Outcome
Pain score measured using the numeric rating scale for pain: 0=no pain and 10=worst imaginable pain
Interventions
- DEVICE Cryoneurolysis
- DEVICE Sham comparator
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 4 participants |
| Start Date | 2019-04-20 |
| Est. Completion | 2020-03-25 |
| Phase | NA |
Why NCT03917823 stopped before completion
NCT03917823 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 4 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (100% lower).
The record links to 0 conditions, and to 2 interventions - of which Cryoneurolysis is the first listed.
NCT03917823 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT03917823 about?
NCT03917823 is a clinical study titled "Intercostal Cryoneurolysis Following Traumatic Rib Fractures". Rib fractures are one of the most common injuries in trauma patients. These fractures are associated with significant pain as well as decreased ability to inspire deeply or cough to clear secretions, which together lead to pulmonary complications and a high degree of morbidity and mortality. Periphe...
What is the current status of trial NCT03917823?
This trial is currently terminated. It is a NA study. The enrollment target is 4 participants. The study started on 2019-04-20. Estimated completion is 2020-03-25.
What interventions are being tested in trial NCT03917823?
The interventions under investigation include: Cryoneurolysis (DEVICE), Sham comparator (DEVICE).
Who is sponsoring clinical trial NCT03917823?
This trial is sponsored by University of California, San Diego, which has 775 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT03917823's enrollment target sits among peer trials
4 1996th of 2000 higher than 5 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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