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NCT03911453 · ClinicalTrials.gov registry record · Early Phase 1

Window of Opportunity Trial, PARP Inhibitor Rucaparib Affect on PD-L1 Expression in Triple Negative Breast Tumors

A Early Phase 1 study, sponsored by University of Arizona.

Completed
Registry status
Early Phase 1
Development phase
20
Enrollment target

NCT03911453 is a Early Phase 1 study that has completed, run by University of Arizona. The registered enrollment target is 20 participants.

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The verdict

NCT03911453, a Early Phase 1 study, has completed, sponsored by University of Arizona.

COMPLETED
Registry status
Early Phase 1
Development phase
20 participants
Enrollment target

Study Summary

This is a single arm window of opportunity trial conducted in patients with early stage triple negative breast tumors to evaluate if treatment with a Poly(ADP-ribose) polymerase (PARP) inhibitor will increase expression of programmed cell death-1 with ligand (PD-L1) in triple negative breast tumors.

Interventions

  • DRUG Rucaparib

Trial Details

FieldValue
Enrollment Target 20 participants
Start Date 2019-04-19
Est. Completion 2021-07-16
Phase Early Phase 1

Sponsor

University of Arizona

349 total trials

What the Registry Record Tells You About NCT03911453

The ClinicalTrials.gov registry entry for NCT03911453 describes a study currently listed as completed, categorized as Early Phase 1. The registered enrollment target is 20 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of Arizona, which has 349 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 1 intervention - of which Rucaparib is the first listed.

NCT03911453 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT03911453 about?

NCT03911453 is a clinical study titled "Window of Opportunity Trial, PARP Inhibitor Rucaparib Affect on PD-L1 Expression in Triple Negative Breast Tumors". This is a single arm window of opportunity trial conducted in patients with early stage triple negative breast tumors to evaluate if treatment with a Poly(ADP-ribose) polymerase (PARP) inhibitor will increase expression of programmed cell death-1 with ligand (PD-L1) in triple negative breast tumors.

What is the current status of trial NCT03911453?

This trial is currently completed. It is a Early Phase 1 study. The enrollment target is 20 participants. The study started on 2019-04-19. Estimated completion is 2021-07-16.

What interventions are being tested in trial NCT03911453?

The interventions under investigation include: Rucaparib (DRUG).

Who is sponsoring clinical trial NCT03911453?

This trial is sponsored by University of Arizona, which has 349 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.