Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT03910075 · ClinicalTrials.gov registry record · Phase 3
Perinatal Arterial Stroke: A Multi-site RCT of Intensive Infant Rehabilitation (I-ACQUIRE)
A Phase 3 study, sponsored by Virginia Polytechnic Institute and State University.
- Completed
- Registry status
- Phase 3
- Development phase
- 216
- Enrollment target
NCT03910075: Completed Phase 3 study, sponsored by Virginia Polytechnic Institute and State University.
NCT03910075 is a Phase 3 study that has completed, run by Virginia Polytechnic Institute and State University. The registered enrollment target is 216 participants, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (72% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03910075, a Phase 3 study, has completed, sponsored by Virginia Polytechnic Institute and State University.
- COMPLETED
- Registry status
- Phase 3
- Development phase
- 216 participants
- Enrollment target
Study Summary
This is a Phase III clinical trial to compare the efficacy of two dosages of a new infant rehabilitation protocol - I-ACQUIRE - to usual and customary forms of infant rehabilitation in infants who experienced Perinatal Arterial Stroke (PAS).
Primary Outcome
The primary efficacy is measured by the Emerging Behaviors Scale (EBS) that counts the number of upper extremity skills on the hemiparetic side that the child displays (from 0 to 30). The source for observation comes from a battery of standardized age-appropriate neuromotor assessment tools (Gross Motor Function Measure-66, The Bayley III Fine and Gross Motor scales, unilateral skills during the Mini AHA) and independent observational coding of the videotaped assessment session with supplemental
Interventions
- BEHAVIORAL I-ACQUIRE - High Dosage
- BEHAVIORAL I-ACQUIRE - Moderate Dosage
- BEHAVIORAL Usual & Customary Treatment (U&CT)
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 216 participants |
| Start Date | 2019-10-10 |
| Est. Completion | 2025-07-31 |
| Phase | Phase 3 |
What the finished NCT03910075 record still lists
NCT03910075 is an interventional study that assigns participants to a tested intervention. The registered 216 participants enrollment target is mid-sized for trials with a published cap, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (72% lower).
The record links to 0 conditions, and to 3 interventions - of which I-ACQUIRE - High Dosage is the first listed.
NCT03910075 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT03910075 about?
NCT03910075 is a clinical study titled "Perinatal Arterial Stroke: A Multi-site RCT of Intensive Infant Rehabilitation (I-ACQUIRE)". This is a Phase III clinical trial to compare the efficacy of two dosages of a new infant rehabilitation protocol - I-ACQUIRE - to usual and customary forms of infant rehabilitation in infants who experienced Perinatal Arterial Stroke (PAS).
What is the current status of trial NCT03910075?
This trial is currently completed. It is a Phase 3 study. The enrollment target is 216 participants. The study started on 2019-10-10. Estimated completion is 2025-07-31.
What interventions are being tested in trial NCT03910075?
The interventions under investigation include: I-ACQUIRE - High Dosage (BEHAVIORAL), I-ACQUIRE - Moderate Dosage (BEHAVIORAL), Usual & Customary Treatment (U&CT) (BEHAVIORAL).
Who is sponsoring clinical trial NCT03910075?
This trial is sponsored by Virginia Polytechnic Institute and State University, which has 104 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT03910075's enrollment target sits among peer trials
216 1332nd of 2000 higher than 667 of 2,000 other Phase 3 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 3 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT02609685 · 216 participants · NA
Active Surveillance of Papillary Thyroid Microcarcinoma
- NCT04994873 · 216 participants · NA
Skills to Enhance Positivity in Suicidal Youth
- NCT05264779 · 216 participants · NA
The Periviable GOALS Decision Support Tool
- NCT05434130 · 216 participants · Phase 2
Modulating Exercise Dosage to Improve Concussion Recovery
Similar registry start date
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia
- NCT07125183 · started 2026-12 · Phase 2
Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma
- NCT07292298 · started 2026-11 · Phase 2
Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates
- NCT04263285 · started 2026-10 · NA
Treatment of Depression Post-SCI