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NCT03903640 · ClinicalTrials.gov registry record · Phase 2

Optune Device - TT Field Plus Nivolumab and Ipilimumab for Melanoma With Brain Metastasis

A Phase 2 study, sponsored by Washington University School of Medicine.

Terminated
Registry status
Phase 2
Development phase
2
Enrollment target

NCT03903640 is a Phase 2 study that was terminated before completion, run by Washington University School of Medicine. The registered enrollment target is 2 participants.

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The verdict

NCT03903640, a Phase 2 study, was terminated before completion, sponsored by Washington University School of Medicine.

TERMINATED
Registry status
Phase 2
Development phase
2 participants
Enrollment target

Study Summary

This phase II study will evaluate the safety of combining intermediate frequency electric field (TT Field) with immunotherapy in melanoma patients with brain metastasis. The data of this study will also inform whether this combination will offer advantage in progression free survival (PFS) and overall survival.

Interventions

  • BIOLOGICAL Nivolumab
  • BIOLOGICAL Ipilimumab
  • DEVICE Optune

Trial Details

FieldValue
Enrollment Target 2 participants
Start Date 2019-10-14
Est. Completion 2021-11-03
Phase Phase 2

What the Registry Record Tells You About NCT03903640

The ClinicalTrials.gov registry entry for NCT03903640 describes a study currently listed as terminated, categorized as Phase 2. The registered enrollment target is 2 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Washington University School of Medicine, which has 1,502 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 3 interventions - of which Nivolumab is the first listed.

NCT03903640 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT03903640 about?

NCT03903640 is a clinical study titled "Optune Device - TT Field Plus Nivolumab and Ipilimumab for Melanoma With Brain Metastasis". This phase II study will evaluate the safety of combining intermediate frequency electric field (TT Field) with immunotherapy in melanoma patients with brain metastasis. The data of this study will also inform whether this combination will offer advantage in progression free survival (PFS) and overa...

What is the current status of trial NCT03903640?

This trial is currently terminated. It is a Phase 2 study. The enrollment target is 2 participants. The study started on 2019-10-14. Estimated completion is 2021-11-03.

What interventions are being tested in trial NCT03903640?

The interventions under investigation include: Nivolumab (BIOLOGICAL), Ipilimumab (BIOLOGICAL), Optune (DEVICE).

Who is sponsoring clinical trial NCT03903640?

This trial is sponsored by Washington University School of Medicine, which has 1,502 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.