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NCT03903549 · ClinicalTrials.gov registry record · Phase 1

Initial Investigation of [18F]P17-059 in Parkinson's Disease Patients and Healthy Volunteers

A Phase 1 study, sponsored by Five Eleven Pharma.

Completed
Registry status
Phase 1
Development phase
4
Enrollment target

NCT03903549: Completed Phase 1 study, sponsored by Five Eleven Pharma.

NCT03903549 is a Phase 1 study that has completed, run by Five Eleven Pharma. The registered enrollment target is 4 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (93% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT03903549, a Phase 1 study, has completed, sponsored by Five Eleven Pharma.

COMPLETED
Registry status
Phase 1
Development phase
4 participants
Enrollment target

Study Summary

This study investigates the initial safety profile of \[18F\]P17-059 in healthy volunteers including dosimetry determination, and compares regional brain uptake and kinetics of \[18F\]P17-059 in Parkinson's disease patients with regional brain uptake and kinetics of \[18F\]P17-059 in healthy volunteers.

Primary Outcome

Quantitative estimates of \[18F\]P17-059 uptake in brain - SUV and non-displaceable Binding Potential

Interventions

  • DRUG [18F]P17-059

Trial Details

FieldValue
Enrollment Target 4 participants
Start Date 2022-07-15
Est. Completion 2022-12-19
Phase Phase 1
Five Eleven Pharma

6 total trials

What the finished NCT03903549 record still lists

NCT03903549 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 4 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (93% lower).

The record links to 0 conditions, and to 1 intervention - of which [18F]P17-059 is the first listed.

NCT03903549 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT03903549 about?

NCT03903549 is a clinical study titled "Initial Investigation of [18F]P17-059 in Parkinson's Disease Patients and Healthy Volunteers". This study investigates the initial safety profile of \[18F\]P17-059 in healthy volunteers including dosimetry determination, and compares regional brain uptake and kinetics of \[18F\]P17-059 in Parkinson's disease patients with regional brain uptake and kinetics of \[18F\]P17-059 in healthy volunte...

What is the current status of trial NCT03903549?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 4 participants. The study started on 2022-07-15. Estimated completion is 2022-12-19.

What interventions are being tested in trial NCT03903549?

The interventions under investigation include: [18F]P17-059 (DRUG).

Who is sponsoring clinical trial NCT03903549?

This trial is sponsored by Five Eleven Pharma, which has 6 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT03903549's enrollment target sits among peer trials

4 1995th of 2000 higher than 2 of 2,000 other Phase 1 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT03903549, the US trial registry maintained by the National Library of Medicine. NCT03903549 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.