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NCT03897699 · ClinicalTrials.gov registry record · NA
Mindful Breathing and tDCS for Depression
A NA study, sponsored by University of Minnesota.
- Completed
- Registry status
- NA
- Development phase
- 68
- Enrollment target
NCT03897699: Completed NA study, sponsored by University of Minnesota.
NCT03897699 is a NA study that has completed, run by University of Minnesota. The registered enrollment target is 68 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (95% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03897699, a NA study, has completed, sponsored by University of Minnesota.
- COMPLETED
- Registry status
- NA
- Development phase
- 68 participants
- Enrollment target
Study Summary
This study will investigate whether transcranial direct current stimulation (tDCS) targeting the dorsolateral prefrontal cortex (DLPFC) can enhance the therapeutic effect of mindful breathing training (MBT) for adolescent depression. The objective is to enhance connectivity between the DLPFC with the amygdala and Default Mode Network (DMN) circuits as well as to enhance emotion regulation abilities and decrease rumination to reduce symptoms of depression. This will aid in the development of novel treatments for depression.
Primary Outcome
Change in dorsolateral prefrontal cortex connectivity with the salience network and the default mode using functional MRI compared between treatment groups: Right Amygdala and left DLPFC. Lower connectivity may represent a reduced tendency to engage in maladaptive, repetitive negative thinking. For r-values, 0 represents that the timeseries of the respective ROIs are not correlated. A better outcome may be indexed by lower connectivity (e.g., negative R values), which may represent a greater ab
Interventions
- OTHER Sham
- DEVICE Transcranial Direct Current Stimulation
- BEHAVIORAL Mindful Breathing
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 68 participants |
| Start Date | 2019-03-01 |
| Est. Completion | 2021-10-01 |
| Phase | NA |
What the finished NCT03897699 record still lists
NCT03897699 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 68 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (95% lower).
The record links to 0 conditions, and to 3 interventions - of which Sham is the first listed.
NCT03897699 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT03897699 about?
NCT03897699 is a clinical study titled "Mindful Breathing and tDCS for Depression". This study will investigate whether transcranial direct current stimulation (tDCS) targeting the dorsolateral prefrontal cortex (DLPFC) can enhance the therapeutic effect of mindful breathing training (MBT) for adolescent depression. The objective is to enhance connectivity between the DLPFC with th...
What is the current status of trial NCT03897699?
This trial is currently completed. It is a NA study. The enrollment target is 68 participants. The study started on 2019-03-01. Estimated completion is 2021-10-01.
What interventions are being tested in trial NCT03897699?
The interventions under investigation include: Sham (OTHER), Transcranial Direct Current Stimulation (DEVICE), Mindful Breathing (BEHAVIORAL).
Who is sponsoring clinical trial NCT03897699?
This trial is sponsored by University of Minnesota, which has 966 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT03897699's enrollment target sits among peer trials
68 1133rd of 2000 higher than 862 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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