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NCT03894618 · ClinicalTrials.gov registry record · Phase 1

SL-279252 (PD1-Fc-OX40L) in Subjects With Advanced Solid Tumors or Lymphomas

A Phase 1 study, sponsored by Shattuck Labs.

Completed
Registry status
Phase 1
Development phase
49
Enrollment target

NCT03894618: Completed Phase 1 study, sponsored by Shattuck Labs.

NCT03894618 is a Phase 1 study that has completed, run by Shattuck Labs. The registered enrollment target is 49 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (18% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT03894618, a Phase 1 study, has completed, sponsored by Shattuck Labs.

COMPLETED
Registry status
Phase 1
Development phase
49 participants
Enrollment target

Study Summary

This is a Phase 1 first in human, open label, multi-center, dose escalation and dose expansion study to evaluate the safety, tolerability, PK, anti-tumor activity and pharmacodynamic effects of SL-279252 in subjects with advanced solid tumors or lymphomas.

Primary Outcome

Number of participants with treatment emergent adverse events

Interventions

  • DRUG SL-279252

Trial Details

FieldValue
Enrollment Target 49 participants
Start Date 2019-03-26
Est. Completion 2023-05-04
Phase Phase 1
Shattuck Labs

6 total trials

What the finished NCT03894618 record still lists

NCT03894618 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 49 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (18% lower).

The record links to 0 conditions, and to 1 intervention - of which SL-279252 is the first listed.

NCT03894618 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT03894618 about?

NCT03894618 is a clinical study titled "SL-279252 (PD1-Fc-OX40L) in Subjects With Advanced Solid Tumors or Lymphomas". This is a Phase 1 first in human, open label, multi-center, dose escalation and dose expansion study to evaluate the safety, tolerability, PK, anti-tumor activity and pharmacodynamic effects of SL-279252 in subjects with advanced solid tumors or lymphomas.

What is the current status of trial NCT03894618?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 49 participants. The study started on 2019-03-26. Estimated completion is 2023-05-04.

What interventions are being tested in trial NCT03894618?

The interventions under investigation include: SL-279252 (DRUG).

Who is sponsoring clinical trial NCT03894618?

This trial is sponsored by Shattuck Labs, which has 6 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT03894618's enrollment target sits among peer trials

49 1017th of 2000 higher than 976 of 2,000 other Phase 1 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT03894618, the US trial registry maintained by the National Library of Medicine. NCT03894618 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.