Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT03894553 · ClinicalTrials.gov registry record · NA

Focused Ultrasound (FUS) Mesencephalotomy for Head & Neck Cancer Pain

A NA study, sponsored by Jeff Elias, MD.

Completed
Registry status
NA
Development phase
6
Enrollment target

NCT03894553: Completed NA study, sponsored by Jeff Elias, MD.

NCT03894553 is a NA study that has completed, run by Jeff Elias, MD. The registered enrollment target is 6 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (100% lower). According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

View your shortlist →

The verdict

NCT03894553, a NA study, has completed, sponsored by Jeff Elias, MD.

COMPLETED
Registry status
NA
Development phase
6 participants
Enrollment target

Study Summary

This proposed pilot study will investigate the safety and initial effectiveness of focused ultrasound lesioning of the contralateral mesencephalon for severe, opioid-resistant pain associated with head and neck cancer

Primary Outcome

Number of participants with treatment-related adverse events, as assessed from adverse event reporting throughout the 6 month study period. Additional measures of safety will be made with MRI evaluation.

Interventions

  • DEVICE ExAblate Neuro

Trial Details

FieldValue
Enrollment Target 6 participants
Start Date 2020-06-22
Est. Completion 2025-08-31
Phase NA
Jeff Elias, MD

2 total trials

What the finished NCT03894553 record still lists

NCT03894553 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 6 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (100% lower).

The record links to 0 conditions, and to 1 intervention - of which ExAblate Neuro is the first listed.

NCT03894553 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT03894553 about?

NCT03894553 is a clinical study titled "Focused Ultrasound (FUS) Mesencephalotomy for Head & Neck Cancer Pain". This proposed pilot study will investigate the safety and initial effectiveness of focused ultrasound lesioning of the contralateral mesencephalon for severe, opioid-resistant pain associated with head and neck cancer

What is the current status of trial NCT03894553?

This trial is currently completed. It is a NA study. The enrollment target is 6 participants. The study started on 2020-06-22. Estimated completion is 2025-08-31.

What interventions are being tested in trial NCT03894553?

The interventions under investigation include: ExAblate Neuro (DEVICE).

Who is sponsoring clinical trial NCT03894553?

This trial is sponsored by Jeff Elias, MD, which has 2 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT03894553's enrollment target sits among peer trials

6 1983rd of 2000 higher than 13 of 2,000 other NA trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

Nationwide trials with similar profiles

Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.

Similar registry start date

  • NCT05962346 · started 2026-12 · NA

    Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia

  • NCT07125183 · started 2026-12 · Phase 2

    Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma

  • NCT07292298 · started 2026-11 · Phase 2

    Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates

  • NCT04263285 · started 2026-10 · NA

    Treatment of Depression Post-SCI

Source: ClinicalTrials.gov NCT03894553, the US trial registry maintained by the National Library of Medicine. NCT03894553 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.