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RejuvenAir® System Trial for COPD With Chronic Bronchitis
NCT03893370 · View on ClinicalTrials.gov ↗
Study Summary
Chronic Obstructive Pulmonary Disease (COPD) is defined as an impaired ability to move air within the lungs and is a major public health problem that is projected to rank fifth worldwide in terms of disease burden and third in terms of mortality. Chronic bronchitis (CB) is a common clinical phenotype within the umbrella of a COPD diagnosis and is classically defined as chronic cough and sputum production for 3 months a year for 2 consecutive years2, but many studies have used different definitions to define it- chronic cough and sputum production for one year or cough and sputum production on most days of the week. CB is associated with multiple clinical consequences, including; the worsening of lung function decline, increasing risk of acute exacerbations of COPD, increased risk of developing pneumonia, reduced health related quality of life, and an increase in all-cause mortality.
Conditions Studied
Interventions
- DEVICE RejuvenAir System
- DEVICE Sham Control Procedure
Study Locations (20)
Ohio
- University Of Cincinnati — Cincinnati
- The Cleveland Clinic Foundation — Cleveland
- The Ohio State Universisty — Columbus
California
- El Camino Hospital — Mountain View
- University of California, Davis Medical Center — Sacramento
Florida
- Advanced Pulmonary Research Institute — Loxahatchee Groves
- Sarasota Memorial Hospital — Sarasota
Maryland
- University of Maryland — Baltimore
- Johns Hopkins Universtiy — Baltimore
Michigan
- Henry Ford Health System — Detroit
- Spectrum Health — Grand Rapids
Pennsylvania
- Clinical Research Associates of Central PA — Altoona
- Temple University - Of the Commonwealth System of Higher Education — Philadelphia
Arizona
- Honor Health — Scottsdale
Illinois
- Northwestern University — Chicago
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 210 participants |
| Start Date | 2020-07-09 |
| Est. Completion | 2026-09 |
| Phase | NA |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT03893370
The ClinicalTrials.gov registry entry for NCT03893370 describes a study currently listed as active not recruiting. It is categorized as NA, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 210 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is CSA Medical, which has 2 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.
The record links to 1 condition, with Chronic Bronchitis appearing as the primary indexed condition, and to 2 interventions — of which RejuvenAir System is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.
Geographic footprint matters for practical reasons: NCT03893370 reports 20 study locations spanning 13 distinct geographic areas — top geographies include Ohio, California, Florida. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.
Frequently Asked Questions
What is clinical trial NCT03893370 about?
NCT03893370 is a clinical study titled "RejuvenAir® System Trial for COPD With Chronic Bronchitis". Chronic Obstructive Pulmonary Disease (COPD) is defined as an impaired ability to move air within the lungs and is a major public health problem that is projected to rank fifth worldwide in terms of disease burden and third in terms of mortality. Chronic bronchitis (CB) is a common clinical phenotyp...
What is the current status of trial NCT03893370?
This trial is currently active not recruiting. It is a NA study. The enrollment target is 210 participants. The study started on 2020-07-09. Estimated completion is 2026-09.
What conditions does trial NCT03893370 study?
This clinical trial studies the following conditions: Chronic Bronchitis. These conditions were identified from the trial registry and reflect the primary focus areas of the research.
What interventions are being tested in trial NCT03893370?
The interventions under investigation include: RejuvenAir System (DEVICE), Sham Control Procedure (DEVICE). Each intervention is being evaluated for safety and efficacy as part of this clinical study.
Who is sponsoring clinical trial NCT03893370?
This trial is sponsored by CSA Medical, which has 2 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.
Where is trial NCT03893370 being conducted?
This trial has 20 study locations across Arizona, California, Florida, Illinois, Louisiana. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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