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NCT03893175 · ClinicalTrials.gov registry record · Phase 1
Towards Predicting the Analgesic Response to Ibuprofen Following Third-molar Extraction
A Phase 1 study, sponsored by University of Pennsylvania.
- Completed
- Registry status
- Phase 1
- Development phase
- 86
- Enrollment target
NCT03893175: Completed Phase 1 study, sponsored by University of Pennsylvania.
NCT03893175 is a Phase 1 study that has completed, run by University of Pennsylvania. The registered enrollment target is 86 participants, above the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (43% higher). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03893175, a Phase 1 study, has completed, sponsored by University of Pennsylvania.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 86 participants
- Enrollment target
Study Summary
This research study will evaluate inter-individual variability in the analgesic response to the non-steroidal anti-inflammatory drug (NSAID) ibuprofen after third molar extraction surgery. It will also investigate demographic, clinical, genetic, and environmental factors that cause this variability.
Primary Outcome
Use of opioid rescue medication
Interventions
- DRUG Placebo
- DRUG Acetaminophen
- DRUG Ibuprofen
- DRUG Oxycodone
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 86 participants |
| Start Date | 2019-05-10 |
| Est. Completion | 2022-03-02 |
| Phase | Phase 1 |
What the finished NCT03893175 record still lists
NCT03893175 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 86 participants, a relatively small participant target, above the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (43% higher).
The record links to 0 conditions, and to 4 interventions - of which Placebo is the first listed.
NCT03893175 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT03893175 about?
NCT03893175 is a clinical study titled "Towards Predicting the Analgesic Response to Ibuprofen Following Third-molar Extraction". This research study will evaluate inter-individual variability in the analgesic response to the non-steroidal anti-inflammatory drug (NSAID) ibuprofen after third molar extraction surgery. It will also investigate demographic, clinical, genetic, and environmental factors that cause this variability.
What is the current status of trial NCT03893175?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 86 participants. The study started on 2019-05-10. Estimated completion is 2022-03-02.
What interventions are being tested in trial NCT03893175?
The interventions under investigation include: Placebo (DRUG), Acetaminophen (DRUG), Ibuprofen (DRUG), Oxycodone (DRUG).
Who is sponsoring clinical trial NCT03893175?
This trial is sponsored by University of Pennsylvania, which has 1,423 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT03893175's enrollment target sits among peer trials
86 652nd of 2000 higher than 1,345 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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