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NCT03883880 · ClinicalTrials.gov registry record · NA
Salivary Interactions With Chemosensations
A NA study, sponsored by Purdue University.
- Terminated
- Registry status
- NA
- Development phase
- 32
- Enrollment target
NCT03883880: Clinical Trial NA study, sponsored by Purdue University.
NCT03883880 is a NA study that was terminated before completion, run by Purdue University. The registered enrollment target is 32 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (98% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03883880, a NA study, was terminated before completion, sponsored by Purdue University.
- TERMINATED
- Registry status
- NA
- Development phase
- 32 participants
- Enrollment target
Study Summary
A counterbalanced, crossover design will be used to evaluate whether exposure to flavors vs. a control over time alters the perception of the flavor by changing an individual's salivary protein profile. Participants will complete 3 acute tasting protocols (baseline, after intervention 1, after intervention 2). The interventions will be with the flavor (epigallocatechin gallate, linolenic acid, capsaicin) or a control, in counterbalanced order, and will involve swishing and swallowing a solution of that sample 5 times per day for two weeks. Each of these flavors will be a separate sub-study.
Primary Outcome
Subjects saliva will be collected at baseline, after the flavor intervention, and after control intervention (two weeks each, order counterbalanced) for each type of intervention (epigallocatechin gallate, linoleic acid, capsaicin). The proteomic composition of the saliva samples will be established, and used to evaluate relationships with other outcome measures.
Interventions
- OTHER Epigallocatechin gallate
- OTHER Epigallocatechin gallate control
- OTHER Linoleic acid
- OTHER Linoleic acid control
- OTHER Capsaicin solution
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 32 participants |
| Start Date | 2019-01-05 |
| Est. Completion | 2021-12-01 |
| Phase | NA |
Why NCT03883880 stopped before completion
NCT03883880 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 32 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (98% lower).
The record links to 0 conditions, and to 5 interventions - of which Epigallocatechin gallate is the first listed.
NCT03883880 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT03883880 about?
NCT03883880 is a clinical study titled "Salivary Interactions With Chemosensations". A counterbalanced, crossover design will be used to evaluate whether exposure to flavors vs. a control over time alters the perception of the flavor by changing an individual's salivary protein profile. Participants will complete 3 acute tasting protocols (baseline, after intervention 1, after inter...
What is the current status of trial NCT03883880?
This trial is currently terminated. It is a NA study. The enrollment target is 32 participants. The study started on 2019-01-05. Estimated completion is 2021-12-01.
What interventions are being tested in trial NCT03883880?
The interventions under investigation include: Epigallocatechin gallate (OTHER), Epigallocatechin gallate control (OTHER), Linoleic acid (OTHER), Linoleic acid control (OTHER), Capsaicin solution (OTHER).
Who is sponsoring clinical trial NCT03883880?
This trial is sponsored by Purdue University, which has 141 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT03883880's enrollment target sits among peer trials
32 1578th of 2000 higher than 409 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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