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NCT03878381 · ClinicalTrials.gov registry record · Early Phase 1

Investigating the Wrinkle Reduction Potential of a Novel Compounded Skin Care Cream

A Early Phase 1 study of Skin Care, sponsored by Wayne State University.

Completed
Registry status
Early Phase 1
Development phase
10
Enrollment target
1
Study location

NCT03878381 is a Early Phase 1 study of Skin Care that has completed, run by Wayne State University. The registered enrollment target is 10 participants. The trial reports 1 study location across 1 state.

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The verdict

NCT03878381, a Early Phase 1 study of Skin Care, has completed, sponsored by Wayne State University.

COMPLETED
Registry status
Early Phase 1
Development phase
10 participants
Enrollment target
1
Study location

Study Summary

In the realm of cosmetics, skin care accounts for a significant share accounting for 35.3% of the global market, creating a $121 billion industry. While many of the products claim to have unique, natural formulations that boost skin care, many products contain chemicals that are potentially damaging to skin. Such ingredients include preservatives, parabens, fragrances, and formaldehyde, which can cause skin irritation and inflammation. Although these ingredients help to preserve the stability and longevity of products, it is plausible to achieve efficacy and improve skin structure without risking unnecessary damage. The condition and health of the dermis rely largely on elastin, which gives the skin its elasticity, and collagen, which provides structure and strength. Collagen deteriorates naturally with age and exposure to environmental elements such as sunlight and toxins. Many skin rejuvenating interventions have focused on preventing the loss of collagen and elastin. The formulations used in this study will try to optimize cellular physiology, which in turn will create improvement in skin function, collagen strength, and wrinkle depth reduction. The skin care regimen we will be testing includes ingredients such Hyaluronic acid 1%, Vitamin E Acetate, Vitamin A Acetate, Co-enzyme Q 10, L-Arginine, L-glutamine, Phytonadione, Argireline Peptide solution, GABA, Vitamin C, glycolic acid, and Fenugreek. The chemicals used commercially have been avoided in this formulation to enhance the beneficial effects of the product. The purpose of the study is to investigate the efficacy of a new skin care product utilizing the tools of complexion analysis software and optical coherence tomography(OCT). The primary endpoint will be a 15% reduction in facial wrinkles measured by complexion analysis software. Secondary endpoints will be a 10% reduction in skin roughness measured by OCT

Conditions Studied

Interventions

  • DRUG Placebo
  • COMBINATION_PRODUCT Skin Care Cream

Study Locations (1)

Michigan

  • WSUPG Dermatology - Dearborn

Trial Details

FieldValue
Enrollment Target 10 participants
Start Date 2019-04-01
Est. Completion 2022-10-29
Phase Early Phase 1

Sponsor

Wayne State University

163 total trials

What the Registry Record Tells You About NCT03878381

The ClinicalTrials.gov registry entry for NCT03878381 describes a study currently listed as completed, categorized as Early Phase 1. The registered enrollment target is 10 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Wayne State University, which has 163 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Skin Care appearing as the primary indexed condition, and to 2 interventions - of which Placebo is the first listed.

NCT03878381 reports 1 study location spanning 1 distinct geographic area - top geographies include Michigan.

Frequently Asked Questions

What is clinical trial NCT03878381 about?

NCT03878381 is a clinical study titled "Investigating the Wrinkle Reduction Potential of a Novel Compounded Skin Care Cream". In the realm of cosmetics, skin care accounts for a significant share accounting for 35.3% of the global market, creating a $121 billion industry. While many of the products claim to have unique, natural formulations that boost skin care, many products contain chemicals that are potentially damaging...

What is the current status of trial NCT03878381?

This trial is currently completed. It is a Early Phase 1 study. The enrollment target is 10 participants. The study started on 2019-04-01. Estimated completion is 2022-10-29.

What conditions does trial NCT03878381 study?

This clinical trial studies the following conditions: Skin Care.

What interventions are being tested in trial NCT03878381?

The interventions under investigation include: Placebo (DRUG), Skin Care Cream (COMBINATION_PRODUCT).

Who is sponsoring clinical trial NCT03878381?

This trial is sponsored by Wayne State University, which has 163 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT03878381 being conducted?

This trial has 1 study location across Michigan. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

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