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NCT03874793 · ClinicalTrials.gov registry record · NA
Neural Mechanisms of Mindfulness-based Cognitive Therapy (MBCT) for Posttraumatic Stress Disorder (PTSD)
A NA study, sponsored by Ohio State University.
- Completed
- Registry status
- NA
- Development phase
- 61
- Enrollment target
NCT03874793: Completed NA study, sponsored by Ohio State University.
NCT03874793 is a NA study that has completed, run by Ohio State University. The registered enrollment target is 61 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (96% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03874793, a NA study, has completed, sponsored by Ohio State University.
- COMPLETED
- Registry status
- NA
- Development phase
- 61 participants
- Enrollment target
Study Summary
This study will examine the effects of psychotherapy as treatment for PTSD, and specifically how brain activity and brain connectivity is affected by Mindfulness Based Cognitive Therapy (MBCT) and an active mind-body comparison comparison therapy.
Primary Outcome
Posterior cingulate-seed functional connectivity with dorsolateral PFC index (PCC seed-dlPFC rsFC index) was measured using fMRI \[BOLD\] signal, a measure of brain regional blood flow used as a proxy for neural activity. BOLD signal while "resting" identified regions whose activity is correlated with a "seed" ROI within PCC. A whole-brain map of Pearson's (r) was transformed (Fisher r-to-Z) to a T-map. A beta from cluster in the hypothesized dlPFC region was extracted (as the "PCC seed-dlPFC rs
Interventions
- BEHAVIORAL Mindfulness-Based Cognitive Therapy
- BEHAVIORAL Muscle Relaxation Therapy
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 61 participants |
| Start Date | 2019-07-29 |
| Est. Completion | 2024-03-01 |
| Phase | NA |
What the finished NCT03874793 record still lists
NCT03874793 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 61 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (96% lower).
The record links to 0 conditions, and to 2 interventions - of which Mindfulness-Based Cognitive Therapy is the first listed.
NCT03874793 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT03874793 about?
NCT03874793 is a clinical study titled "Neural Mechanisms of Mindfulness-based Cognitive Therapy (MBCT) for Posttraumatic Stress Disorder (PTSD)". This study will examine the effects of psychotherapy as treatment for PTSD, and specifically how brain activity and brain connectivity is affected by Mindfulness Based Cognitive Therapy (MBCT) and an active mind-body comparison comparison therapy.
What is the current status of trial NCT03874793?
This trial is currently completed. It is a NA study. The enrollment target is 61 participants. The study started on 2019-07-29. Estimated completion is 2024-03-01.
What interventions are being tested in trial NCT03874793?
The interventions under investigation include: Mindfulness-Based Cognitive Therapy (BEHAVIORAL), Muscle Relaxation Therapy (BEHAVIORAL).
Who is sponsoring clinical trial NCT03874793?
This trial is sponsored by Ohio State University, which has 552 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT03874793's enrollment target sits among peer trials
61 1164th of 2000 higher than 837 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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