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NCT03873766 · ClinicalTrials.gov registry record · Phase 4
Management of Pleural Space Infections
A Phase 4 study, sponsored by Swedish Medical Center.
- Completed
- Registry status
- Phase 4
- Development phase
- 26
- Enrollment target
NCT03873766: Completed Phase 4 study, sponsored by Swedish Medical Center.
NCT03873766 is a Phase 4 study that has completed, run by Swedish Medical Center. The registered enrollment target is 26 participants, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (95% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03873766, a Phase 4 study, has completed, sponsored by Swedish Medical Center.
- COMPLETED
- Registry status
- Phase 4
- Development phase
- 26 participants
- Enrollment target
Study Summary
Currently, there is no high-quality evidence comparing the clinical outcomes and cost effectiveness of surgical drainage combined with antibiotics versus dual-agent intrapleural fibrinolytic therapy (IPFT) catheter drainage of pleural space infections with concomitant antibiotic therapy. The absence of comparative data is a challenge for surgical and medical services in clinical decision-making for this common and morbid condition. This is a pilot study comparing surgical drainage of the pleural space in complex pleural effusions to bedside chest tube drainage using dual agent IPFT with the intent to inform on study algorithm and endpoint performance in anticipation of a multi-institutional randomized clinical trial.
Primary Outcome
• Test the feasibility of the proposed study algorithm to compare Intrapleural fibrinolytic therapy (IPFT) to surgical intervention as measured by percent enrollment to completion of study algorithm and multidisciplinary participation in adherence to the algorithm.
Interventions
- PROCEDURE Surgery
- DRUG Intrapleural Medications
- PROCEDURE Pleural Sampling
- PROCEDURE Pleural fluid drainage
- RADIATION Protocol Image #1
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 26 participants |
| Start Date | 2019-04-01 |
| Est. Completion | 2022-03-11 |
| Phase | Phase 4 |
What the finished NCT03873766 record still lists
NCT03873766 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 26 participants, a relatively small participant target, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (95% lower).
The record links to 0 conditions, and to 5 interventions - of which Surgery is the first listed.
NCT03873766 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT03873766 about?
NCT03873766 is a clinical study titled "Management of Pleural Space Infections". Currently, there is no high-quality evidence comparing the clinical outcomes and cost effectiveness of surgical drainage combined with antibiotics versus dual-agent intrapleural fibrinolytic therapy (IPFT) catheter drainage of pleural space infections with concomitant antibiotic therapy. The absence...
What is the current status of trial NCT03873766?
This trial is currently completed. It is a Phase 4 study. The enrollment target is 26 participants. The study started on 2019-04-01. Estimated completion is 2022-03-11.
What interventions are being tested in trial NCT03873766?
The interventions under investigation include: Surgery (PROCEDURE), Intrapleural Medications (DRUG), Pleural Sampling (PROCEDURE), Pleural fluid drainage (PROCEDURE), Protocol Image #1 (RADIATION).
Who is sponsoring clinical trial NCT03873766?
This trial is sponsored by Swedish Medical Center, which has 30 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT03873766's enrollment target sits among peer trials
26 1655th of 2000 higher than 332 of 2,000 other Phase 4 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 4 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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