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NCT03852719 · ClinicalTrials.gov registry record · Phase 3

Study to Assess Efficacy and Safety of Bulevirtide in Participants With Chronic Hepatitis Delta (CHD)

A Phase 3 study, sponsored by Gilead Sciences.

Completed
Registry status
Phase 3
Development phase
150
Enrollment target

NCT03852719 is a Phase 3 study that has completed, run by Gilead Sciences. The registered enrollment target is 150 participants.

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The verdict

NCT03852719, a Phase 3 study, has completed, sponsored by Gilead Sciences.

COMPLETED
Registry status
Phase 3
Development phase
150 participants
Enrollment target

Study Summary

The primary objective of this study is to evaluate the efficacy of bulevirtide administered subcutaneously (SC) for 48 weeks at a dose of 2 mg or 10 mg once daily for treatment of chronic hepatitis delta (CHD) in comparison to delayed treatment. The main goal of this study is to determine the effectiveness of bulevirtide in participants randomized to bulevirtide 2 mg or 10 mg once daily SC as compared to participants randomized to delayed treatment for 48 weeks. Treatment will continue through Week 144 (participants randomized to delayed treatment will change to bulevirtide 10 mg once daily SC after Week 48 through Week 144). All participants will be followed off-treatment for an additional 96 weeks.

Interventions

  • DRUG Bulevirtide

Trial Details

FieldValue
Enrollment Target 150 participants
Start Date 2019-04-17
Est. Completion 2024-08-08
Phase Phase 3

Sponsor

Gilead Sciences

504 total trials

What the Registry Record Tells You About NCT03852719

The ClinicalTrials.gov registry entry for NCT03852719 describes a study currently listed as completed, categorized as Phase 3. The registered enrollment target is 150 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Gilead Sciences, which has 504 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 1 intervention - of which Bulevirtide is the first listed.

NCT03852719 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT03852719 about?

NCT03852719 is a clinical study titled "Study to Assess Efficacy and Safety of Bulevirtide in Participants With Chronic Hepatitis Delta (CHD)". The primary objective of this study is to evaluate the efficacy of bulevirtide administered subcutaneously (SC) for 48 weeks at a dose of 2 mg or 10 mg once daily for treatment of chronic hepatitis delta (CHD) in comparison to delayed treatment. The main goal of this study is to determine the effec...

What is the current status of trial NCT03852719?

This trial is currently completed. It is a Phase 3 study. The enrollment target is 150 participants. The study started on 2019-04-17. Estimated completion is 2024-08-08.

What interventions are being tested in trial NCT03852719?

The interventions under investigation include: Bulevirtide (DRUG).

Who is sponsoring clinical trial NCT03852719?

This trial is sponsored by Gilead Sciences, which has 504 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.