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NCT03848715 · ClinicalTrials.gov registry record · Phase 1

Sleep and Healthy Aging Research on Depression for Younger Women

A Phase 1 study, sponsored by University of California, Los Angeles.

Completed
Registry status
Phase 1
Development phase
40
Enrollment target

NCT03848715 is a Phase 1 study that has completed, run by University of California, Los Angeles. The registered enrollment target is 40 participants.

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The verdict

NCT03848715, a Phase 1 study, has completed, sponsored by University of California, Los Angeles.

COMPLETED
Registry status
Phase 1
Development phase
40 participants
Enrollment target

Study Summary

Compelling evidence indicates inflammation plays a role in depression, but potential mechanisms linking inflammation to depression, such as dysregulated reward processing, are poorly understood. This study comprehensively evaluates effects of inflammation on reward across dimensions (e.g., anticipating versus receiving a reward) and types (e.g., money vs. smiling faces) in younger and older women. Characterizing how inflammation shapes the dynamic and multidimensional reward system, and how this may differ by age, may give insight into risk factors for depression and help identify critical points for intervention.

Interventions

  • BIOLOGICAL Placebo
  • BIOLOGICAL Endotoxin

Trial Details

FieldValue
Enrollment Target 40 participants
Start Date 2019-10-02
Est. Completion 2024-07-22
Phase Phase 1

What the Registry Record Tells You About NCT03848715

The ClinicalTrials.gov registry entry for NCT03848715 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 40 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of California, Los Angeles, which has 897 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 2 interventions - of which Placebo is the first listed.

NCT03848715 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT03848715 about?

NCT03848715 is a clinical study titled "Sleep and Healthy Aging Research on Depression for Younger Women". Compelling evidence indicates inflammation plays a role in depression, but potential mechanisms linking inflammation to depression, such as dysregulated reward processing, are poorly understood. This study comprehensively evaluates effects of inflammation on reward across dimensions (e.g., anticipat...

What is the current status of trial NCT03848715?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 40 participants. The study started on 2019-10-02. Estimated completion is 2024-07-22.

What interventions are being tested in trial NCT03848715?

The interventions under investigation include: Placebo (BIOLOGICAL), Endotoxin (BIOLOGICAL).

Who is sponsoring clinical trial NCT03848715?

This trial is sponsored by University of California, Los Angeles, which has 897 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.