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NCT03829683 · ClinicalTrials.gov registry record · Phase 2
Vitamin C Infusion for TReatment in Sepsis and Alcoholic Hepatitis
A Phase 2 study, sponsored by Virginia Commonwealth University.
- Completed
- Registry status
- Phase 2
- Development phase
- 20
- Enrollment target
NCT03829683: Completed Phase 2 study, sponsored by Virginia Commonwealth University.
NCT03829683 is a Phase 2 study that has completed, run by Virginia Commonwealth University. The registered enrollment target is 20 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (85% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03829683, a Phase 2 study, has completed, sponsored by Virginia Commonwealth University.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 20 participants
- Enrollment target
Study Summary
The purpose of this research study is to test the safety, tolerability, and effectiveness of Vitamin C (ascorbic acid) intravenous infusion when used to treat alcoholic hepatitis (inflammation of the liver from heavy alcohol use) and sepsis (life-threatening complication of an infection).
Primary Outcome
Change in MELD score from Day 0 to Day 4. MELD score ranges from 6 (least sick) to 40 (most sick) based on blood tests which ranks the degree of sickness from liver disease. The lab tests used to determine the MELD score are creatinine, bilirubin, and international normalized ratio (INR).
Interventions
- DRUG Vitamin C
- DRUG Dextrose 5% in water
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 20 participants |
| Start Date | 2019-04-16 |
| Est. Completion | 2022-06-23 |
| Phase | Phase 2 |
What the finished NCT03829683 record still lists
NCT03829683 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 20 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (85% lower).
The record links to 0 conditions, and to 2 interventions - of which Vitamin C is the first listed.
NCT03829683 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT03829683 about?
NCT03829683 is a clinical study titled "Vitamin C Infusion for TReatment in Sepsis and Alcoholic Hepatitis". The purpose of this research study is to test the safety, tolerability, and effectiveness of Vitamin C (ascorbic acid) intravenous infusion when used to treat alcoholic hepatitis (inflammation of the liver from heavy alcohol use) and sepsis (life-threatening complication of an infection).
What is the current status of trial NCT03829683?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 20 participants. The study started on 2019-04-16. Estimated completion is 2022-06-23.
What interventions are being tested in trial NCT03829683?
The interventions under investigation include: Vitamin C (DRUG), Dextrose 5% in water (DRUG).
Who is sponsoring clinical trial NCT03829683?
This trial is sponsored by Virginia Commonwealth University, which has 558 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT03829683's enrollment target sits among peer trials
20 1805th of 2000 higher than 107 of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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