Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT03820726 · ClinicalTrials.gov registry record · Phase 3

A Follow-up Study Investigating Long Term Treatment With Nintedanib in Patients With Progressive Fibrosing Interstitial Lung Disease (PF-ILD)

A Phase 3 study, sponsored by Boehringer Ingelheim.

Completed
Registry status
Phase 3
Development phase
435
Enrollment target

NCT03820726: Completed Phase 3 study, sponsored by Boehringer Ingelheim.

NCT03820726 is a Phase 3 study that has completed, run by Boehringer Ingelheim. The registered enrollment target is 435 participants, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (44% lower). According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

View your shortlist →

The verdict

NCT03820726, a Phase 3 study, has completed, sponsored by Boehringer Ingelheim.

COMPLETED
Registry status
Phase 3
Development phase
435 participants
Enrollment target

Study Summary

The main objective is to assess long term tolerability and safety of treatment with oral nintedanib in patients with Progressive Fibrosing Interstitial Lung Disease (PF-ILD) who have complete (and did not prematurely discontinue trial medication in) the phase III parent trial, INBUILD® (trial 1199.247).

Primary Outcome

Number of participants with adverse events over the course of the extension trial, AEs defined as any untoward medical occurrence in a patient administered with the investigational product and which does not necessarily have to have a causal relationship with this treatment.

Interventions

  • DRUG Nintedanib

Trial Details

FieldValue
Enrollment Target 435 participants
Start Date 2019-04-16
Est. Completion 2022-08-30
Phase Phase 3
Boehringer Ingelheim

515 total trials

What the finished NCT03820726 record still lists

NCT03820726 is an interventional study that assigns participants to a tested intervention. The registered 435 participants enrollment target is mid-sized for trials with a published cap, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (44% lower).

The record links to 0 conditions, and to 1 intervention - of which Nintedanib is the first listed.

NCT03820726 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT03820726 about?

NCT03820726 is a clinical study titled "A Follow-up Study Investigating Long Term Treatment With Nintedanib in Patients With Progressive Fibrosing Interstitial Lung Disease (PF-ILD)". The main objective is to assess long term tolerability and safety of treatment with oral nintedanib in patients with Progressive Fibrosing Interstitial Lung Disease (PF-ILD) who have complete (and did not prematurely discontinue trial medication in) the phase III parent trial, INBUILD® (trial 1199.2...

What is the current status of trial NCT03820726?

This trial is currently completed. It is a Phase 3 study. The enrollment target is 435 participants. The study started on 2019-04-16. Estimated completion is 2022-08-30.

What interventions are being tested in trial NCT03820726?

The interventions under investigation include: Nintedanib (DRUG).

Who is sponsoring clinical trial NCT03820726?

This trial is sponsored by Boehringer Ingelheim, which has 515 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT03820726's enrollment target sits among peer trials

435 875th of 2000 higher than 1,125 of 2,000 other Phase 3 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 3 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

Nationwide trials with similar profiles

Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.

Similar enrollment target

  • NCT05563220 · 435 participants · Phase 1

    Open-Label Umbrella Study To Evaluate Safety And Efficacy Of Elacestrant In Various Combination In Participants With Metastatic Breast Cancer

  • NCT07088926 · 435 participants · Phase 2

    A Study to Evaluate the Efficacy, Safety, and PK of AZD0292 Administered IV in Participants 12 Years of Age and Older With Bronchiectasis and Chronic Pseudomonas Aeruginosa Colonization

  • NCT02622542 · 436 participants · NA

    ACute Uncomplicated Type b Aortic Dissection: Endovascular Repair vs. Best Medical Therapy

  • NCT05918211 · 436 participants · Phase 3

    Fontan Udenafil Exercise Longitudinal Assessment Trial - 2

Similar registry start date

  • NCT05962346 · started 2026-12 · NA

    Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia

  • NCT07125183 · started 2026-12 · Phase 2

    Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma

  • NCT07292298 · started 2026-11 · Phase 2

    Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates

  • NCT04263285 · started 2026-10 · NA

    Treatment of Depression Post-SCI

Source: ClinicalTrials.gov NCT03820726, the US trial registry maintained by the National Library of Medicine. NCT03820726 (mid enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.