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NCT03812679 · ClinicalTrials.gov registry record · NA

Performance Evaluation of the AMIA APD Solution Generation System in Patients End Stage Renal Disease (ESRD)

A NA study, sponsored by Vantive Health.

Terminated
Registry status
NA
Development phase
22
Enrollment target

NCT03812679: Clinical Trial NA study, sponsored by Vantive Health.

NCT03812679 is a NA study that was terminated before completion, run by Vantive Health. The registered enrollment target is 22 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (98% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT03812679, a NA study, was terminated before completion, sponsored by Vantive Health.

TERMINATED
Registry status
NA
Development phase
22 participants
Enrollment target

Study Summary

Peritoneal dialysis (PD) is a well-established treatment for renal failure including long-term management of end stage renal disease (ESRD) by continuous ambulatory peritoneal dialysis or automated peritoneal dialysis (APD). Complementary therapies offer longer term survival for patients with ESRD. However, none of them are devoid of side effects and today their limitations are better understood by the nephrologist. The AMIA APD Solution Generation System combines an updated AMIA APD Cycler with Sharesource Platform (previously cleared) with an in-home water system technology and leverages newly developed AMIA APD Concentrates. The AMIA APD Concentrates, after dilution by the AMIA APD Solution Generation System, are indicated for adult patients in acute or chronic renal failure when non-dialytic medical therapy is judged to be inadequate.

Primary Outcome

The dialysis solution generated by the simulated treatment will be sampled from the heater bag, compared to the specifications of Baxter's approved low calcium Dianeal PD solution. The following 9 test methods will be analyzed: pH at 25 C, Color, 5- (hydroxymethyl)furfural (5HMF), Dextrose hydrous Assay (1.5%, 2.5% or 4.25%), Sodium Lactate Assay, Sodium Assay, Chloride Assay, Magnesium Chloride Hexahydrate (MgCl2.6H2O) Assay, and Calcium Chloride Dihydrate (CaCl2.2H2O) Assay. Measurements were

Interventions

  • DEVICE AMIA APD Solution Generation System

Trial Details

FieldValue
Enrollment Target 22 participants
Start Date 2018-12-20
Est. Completion 2020-02-19
Phase NA
Vantive Health

15 total trials

Why NCT03812679 stopped before completion

NCT03812679 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 22 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (98% lower).

The record links to 0 conditions, and to 1 intervention - of which AMIA APD Solution Generation System is the first listed.

NCT03812679 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT03812679 about?

NCT03812679 is a clinical study titled "Performance Evaluation of the AMIA APD Solution Generation System in Patients End Stage Renal Disease (ESRD)". Peritoneal dialysis (PD) is a well-established treatment for renal failure including long-term management of end stage renal disease (ESRD) by continuous ambulatory peritoneal dialysis or automated peritoneal dialysis (APD). Complementary therapies offer longer term survival for patients with ESRD....

What is the current status of trial NCT03812679?

This trial is currently terminated. It is a NA study. The enrollment target is 22 participants. The study started on 2018-12-20. Estimated completion is 2020-02-19.

What interventions are being tested in trial NCT03812679?

The interventions under investigation include: AMIA APD Solution Generation System (DEVICE).

Who is sponsoring clinical trial NCT03812679?

This trial is sponsored by Vantive Health, which has 15 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT03812679's enrollment target sits among peer trials

22 1756th of 2000 higher than 239 of 2,000 other NA trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT03812679, the US trial registry maintained by the National Library of Medicine. NCT03812679 (small enrollment · none site footprint · terminated) retrieved and formatted by PlainTrial, see methodology.