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NCT03802721 · ClinicalTrials.gov registry record · Early Phase 1
Pharmacokinetics of Benzo[a]Pyrene: Impact of Diet
A Early Phase 1 study, sponsored by Oregon State University.
- Completed
- Registry status
- Early Phase 1
- Development phase
- 7
- Enrollment target
NCT03802721: Completed Early Phase 1 study, sponsored by Oregon State University.
NCT03802721 is a Early Phase 1 study that has completed, run by Oregon State University. The registered enrollment target is 7 participants, below the 53-participant average among 2,764 other Early Phase 1 trials with a reported enrollment target (87% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03802721, a Early Phase 1 study, has completed, sponsored by Oregon State University.
- COMPLETED
- Registry status
- Early Phase 1
- Development phase
- 7 participants
- Enrollment target
Study Summary
Evaluation of the pharmacokinetics for \[14C\]-benzo\[a\]pyrene (\[14C\]-BaP) and metabolites in plasma and urine over 48 hours following a 50 ng dose (5.4 nCi) alone, following 7 days' consumption of Brussels sprouts, and following 7 days' consumption of a supplement containing 3,3'-diindolylmethane (DIM).
Primary Outcome
Determination of highest concentration of 14C-BaP in plasma. Blood samples collected at 0 (baseline), 0.25, 0.5, 1, 2, 3, 4, 8, 24, and 48 hour after dosing. All time points were used to determine Cmax.
Interventions
- DRUG [14C]-benzo[a]pyrene
- DRUG Brussels sprouts before 50 ng dose
- DRUG DIM supplement before 50 ng dose
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 7 participants |
| Start Date | 2019-01-24 |
| Est. Completion | 2024-02-01 |
| Phase | Early Phase 1 |
What the finished NCT03802721 record still lists
NCT03802721 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 7 participants, a relatively small participant target, below the 53-participant average among 2,764 other Early Phase 1 trials with a reported enrollment target (87% lower).
The record links to 0 conditions, and to 3 interventions - of which [14C]-benzo[a]pyrene is the first listed.
NCT03802721 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT03802721 about?
NCT03802721 is a clinical study titled "Pharmacokinetics of Benzo[a]Pyrene: Impact of Diet". Evaluation of the pharmacokinetics for \[14C\]-benzo\[a\]pyrene (\[14C\]-BaP) and metabolites in plasma and urine over 48 hours following a 50 ng dose (5.4 nCi) alone, following 7 days' consumption of Brussels sprouts, and following 7 days' consumption of a supplement containing 3,3'-diindolylmethan...
What is the current status of trial NCT03802721?
This trial is currently completed. It is a Early Phase 1 study. The enrollment target is 7 participants. The study started on 2019-01-24. Estimated completion is 2024-02-01.
What interventions are being tested in trial NCT03802721?
The interventions under investigation include: [14C]-benzo[a]pyrene (DRUG), Brussels sprouts before 50 ng dose (DRUG), DIM supplement before 50 ng dose (DRUG).
Who is sponsoring clinical trial NCT03802721?
This trial is sponsored by Oregon State University, which has 33 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT03802721's enrollment target sits among peer trials
7 1825th of 2000 higher than 156 of 2,000 other Early Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Early Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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