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NCT03790839 · ClinicalTrials.gov registry record · Phase 1
Drug Interaction Study Between Dorzagliatin and Sitagliptin
A Phase 1 study, sponsored by Hua Medicine Limited.
- Completed
- Registry status
- Phase 1
- Development phase
- 15
- Enrollment target
NCT03790839: Completed Phase 1 study, sponsored by Hua Medicine Limited.
NCT03790839 is a Phase 1 study that has completed, run by Hua Medicine Limited. The registered enrollment target is 15 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (75% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03790839, a Phase 1 study, has completed, sponsored by Hua Medicine Limited.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 15 participants
- Enrollment target
Study Summary
This is a Phase 1, open-label, sequential, multiple-dose, drug interaction study of glucokinase activator dorzagliatin and sitagliptin in subjects with T2DM. Pharmacokinetics and pharmacodynamics when dorzagliatin and sitagliptin given alone and in combination will be studied.
Primary Outcome
GMR between combination and sitagliptin monotherapy for Cmax of sitagliptin
Interventions
- DRUG Sitagliptin
- DRUG Dorzagliatin
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 15 participants |
| Start Date | 2019-01-31 |
| Est. Completion | 2019-08-30 |
| Phase | Phase 1 |
What the finished NCT03790839 record still lists
NCT03790839 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 15 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (75% lower).
The record links to 0 conditions, and to 2 interventions - of which Sitagliptin is the first listed.
NCT03790839 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT03790839 about?
NCT03790839 is a clinical study titled "Drug Interaction Study Between Dorzagliatin and Sitagliptin". This is a Phase 1, open-label, sequential, multiple-dose, drug interaction study of glucokinase activator dorzagliatin and sitagliptin in subjects with T2DM. Pharmacokinetics and pharmacodynamics when dorzagliatin and sitagliptin given alone and in combination will be studied.
What is the current status of trial NCT03790839?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 15 participants. The study started on 2019-01-31. Estimated completion is 2019-08-30.
What interventions are being tested in trial NCT03790839?
The interventions under investigation include: Sitagliptin (DRUG), Dorzagliatin (DRUG).
Who is sponsoring clinical trial NCT03790839?
This trial is sponsored by Hua Medicine Limited, which has 6 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT03790839's enrollment target sits among peer trials
15 1798th of 2000 higher than 157 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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