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NCT03788967 · ClinicalTrials.gov registry record · Phase 3

Study to Assess the Efficacy, Safety and Pharmacokinetics of Orally Administered Tebipenem Pivoxil Hydrobromide (SPR994) Compared to Intravenous Ertapenem in Participants With Complicated Urinary Tract Infection (cUTI) or Acute Pyelonephritis (AP)

A Phase 3 study, sponsored by Spero Therapeutics.

Completed
Registry status
Phase 3
Development phase
1,372
Enrollment target

NCT03788967 is a Phase 3 study that has completed, run by Spero Therapeutics. The registered enrollment target is 1,372 participants.

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The verdict

NCT03788967, a Phase 3 study, has completed, sponsored by Spero Therapeutics.

COMPLETED
Registry status
Phase 3
Development phase
1,372 participants
Enrollment target

Study Summary

The key purpose of this study is to evaluate the efficacy, safety and pharmacokinetics (PK) of tebipenem pivoxil hydrobromide (TBPM-PI-HBr) compared to intravenous (IV) ertapenem, in participants with complicated Urinary Tract Infection (cUTI) or Acute Pyelonephritis (AP).

Interventions

  • DRUG Ertapenem
  • DRUG TBPM-PI-HBr
  • DRUG Dummy Infusion
  • DRUG Dummy tablets

Trial Details

FieldValue
Enrollment Target 1,372 participants
Start Date 2019-06-03
Est. Completion 2020-05-27
Phase Phase 3

Sponsor

Spero Therapeutics

14 total trials

What the Registry Record Tells You About NCT03788967

The ClinicalTrials.gov registry entry for NCT03788967 describes a study currently listed as completed, categorized as Phase 3. The registered enrollment target is 1,372 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Spero Therapeutics, which has 14 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 4 interventions - of which Ertapenem is the first listed.

NCT03788967 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT03788967 about?

NCT03788967 is a clinical study titled "Study to Assess the Efficacy, Safety and Pharmacokinetics of Orally Administered Tebipenem Pivoxil Hydrobromide (SPR994) Compared to Intravenous Ertapenem in Participants With Complicated Urinary Tract Infection (cUTI) or Acute Pyelonephritis (AP)". The key purpose of this study is to evaluate the efficacy, safety and pharmacokinetics (PK) of tebipenem pivoxil hydrobromide (TBPM-PI-HBr) compared to intravenous (IV) ertapenem, in participants with complicated Urinary Tract Infection (cUTI) or Acute Pyelonephritis (AP).

What is the current status of trial NCT03788967?

This trial is currently completed. It is a Phase 3 study. The enrollment target is 1,372 participants. The study started on 2019-06-03. Estimated completion is 2020-05-27.

What interventions are being tested in trial NCT03788967?

The interventions under investigation include: Ertapenem (DRUG), TBPM-PI-HBr (DRUG), Dummy Infusion (DRUG), Dummy tablets (DRUG).

Who is sponsoring clinical trial NCT03788967?

This trial is sponsored by Spero Therapeutics, which has 14 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.