Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT03775447 · ClinicalTrials.gov registry record

Fox BioNet Project: ECV-003

A clinical trial, sponsored by Michael J. Fox Foundation for Parkinson's Research.

Completed
Registry status
38
Enrollment target

NCT03775447: Completed study, sponsored by Michael J. Fox Foundation for Parkinson's Research.

NCT03775447 is a clinical trial that has completed, run by Michael J. Fox Foundation for Parkinson's Research. The registered enrollment target is 38 participants. According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

View your shortlist →

The verdict

NCT03775447 has completed, sponsored by Michael J. Fox Foundation for Parkinson's Research.

COMPLETED
Registry status
38 participants
Enrollment target

Study Summary

The goal of this study is to optimize pre-analytical cerebrospinal fluid (CSF) extracellular vesicle isolation protocols for increasing the detection of LRRK2 activity in human CSF

Primary Outcome

For methods involving immunoprecipitation: Increase in peptide spectral matches on mass spectrometry For methods amenable to antibody-based detection: increase in LRRK2 intensity on Western blotting (arbitrary units).

Interventions

  • PROCEDURE Lumbar Puncture

Trial Details

FieldValue
Enrollment Target 38 participants
Start Date 2019-04-23
Est. Completion 2019-12-18

What the finished NCT03775447 record still lists

NCT03775447 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 38 participants, a relatively small participant target.

The record links to 0 conditions, and to 1 intervention - of which Lumbar Puncture is the first listed.

NCT03775447 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT03775447 about?

NCT03775447 is a clinical study titled "Fox BioNet Project: ECV-003". The goal of this study is to optimize pre-analytical cerebrospinal fluid (CSF) extracellular vesicle isolation protocols for increasing the detection of LRRK2 activity in human CSF

What is the current status of trial NCT03775447?

This trial is currently completed. The enrollment target is 38 participants. The study started on 2019-04-23. Estimated completion is 2019-12-18.

What interventions are being tested in trial NCT03775447?

The interventions under investigation include: Lumbar Puncture (PROCEDURE).

Who is sponsoring clinical trial NCT03775447?

This trial is sponsored by Michael J. Fox Foundation for Parkinson's Research, which has 14 total clinical trials registered on ClinicalTrials.gov.

Nationwide trials with similar profiles

Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.

Similar enrollment target

  • NCT01684904 · 38 participants · NA

    Proton Therapy for Esophageal Cancer

  • NCT03310879 · 38 participants · Phase 2

    Study of the CDK4/6 Inhibitor Abemaciclib in Solid Tumors Harboring Genetic Alterations in Genes Encoding D-Type Cyclins or Amplification of CDK4 or CDK6

  • NCT03896269 · 38 participants · Phase 1

    CPX-351 in Treating Patients With Relapsed or Refractory High Risk Myelodysplastic Syndrome or Chronic Myelomonocytic Leukemia

  • NCT04085315 · 38 participants · Phase 1

    Alisertib in Combination With Osimertinib in Metastatic EGFR-mutant Lung Cancer

Similar registry start date

  • NCT05962346 · started 2026-12 · NA

    Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia

  • NCT07125183 · started 2026-12 · Phase 2

    Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma

  • NCT07292298 · started 2026-11 · Phase 2

    Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates

  • NCT04263285 · started 2026-10 · NA

    Treatment of Depression Post-SCI

Source: ClinicalTrials.gov NCT03775447, the US trial registry maintained by the National Library of Medicine. NCT03775447 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.