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NCT03770689 · ClinicalTrials.gov registry record · Phase 1

Study of Peposertib in Combination With Capecitabine and RT in Rectal Cancer

A Phase 1 study, sponsored by EMD Serono Research & Development Institute.

Completed
Registry status
Phase 1
Development phase
19
Enrollment target

NCT03770689 is a Phase 1 study that has completed, run by EMD Serono Research & Development Institute. The registered enrollment target is 19 participants.

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The verdict

NCT03770689, a Phase 1 study, has completed, sponsored by EMD Serono Research & Development Institute.

COMPLETED
Registry status
Phase 1
Development phase
19 participants
Enrollment target

Study Summary

The main purpose of the study was to define maximum tolerated dose (MTD), recommended Phase II dose (RP2D) safety and tolerability of Peposertib in combination with capecitabine and radiotherapy (RT).

Interventions

  • DRUG Capecitabine
  • DRUG Peposertib 50 mg
  • DRUG Peposertib 100 mg
  • DRUG Peposertib 150 mg
  • DRUG Peposertib 250 mg

Trial Details

FieldValue
Enrollment Target 19 participants
Start Date 2019-03-20
Est. Completion 2022-02-21
Phase Phase 1

What the Registry Record Tells You About NCT03770689

The ClinicalTrials.gov registry entry for NCT03770689 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 19 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is EMD Serono Research & Development Institute, which has 81 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 5 interventions - of which Capecitabine is the first listed.

NCT03770689 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT03770689 about?

NCT03770689 is a clinical study titled "Study of Peposertib in Combination With Capecitabine and RT in Rectal Cancer". The main purpose of the study was to define maximum tolerated dose (MTD), recommended Phase II dose (RP2D) safety and tolerability of Peposertib in combination with capecitabine and radiotherapy (RT).

What is the current status of trial NCT03770689?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 19 participants. The study started on 2019-03-20. Estimated completion is 2022-02-21.

What interventions are being tested in trial NCT03770689?

The interventions under investigation include: Capecitabine (DRUG), Peposertib 50 mg (DRUG), Peposertib 100 mg (DRUG), Peposertib 150 mg (DRUG), Peposertib 250 mg (DRUG).

Who is sponsoring clinical trial NCT03770689?

This trial is sponsored by EMD Serono Research & Development Institute, which has 81 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.