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NCT03766581 · ClinicalTrials.gov registry record · Phase 2
A Study on BMS-986177 for the Prevention of a Stroke in Patients Receiving Aspirin and Clopidogrel
A Phase 2 study, sponsored by Bristol-Myers Squibb.
- Completed
- Registry status
- Phase 2
- Development phase
- 2,366
- Enrollment target
NCT03766581: Completed Phase 2 study, sponsored by Bristol-Myers Squibb.
NCT03766581 is a Phase 2 study that has completed, run by Bristol-Myers Squibb. The registered enrollment target is 2,366 participants, above the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (1679% higher). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03766581, a Phase 2 study, has completed, sponsored by Bristol-Myers Squibb.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 2,366 participants
- Enrollment target
Study Summary
The purpose of this clinical study is to determine whether the addition of an oral Factor XIa Inhibitor to Aspirin and Clopidogrel is more effective than standard therapy in secondary stroke prevention.
Primary Outcome
Model based assessment estimate for composite event is a customized statistical analysis called MCP-MOD (Multiple Comparison Procedures, MODel) estimation, which is used to check for dose-response relationship. 95% confidence interval (CI) for composite event based on bootstrap (10000 samples).
Interventions
- OTHER Placebo
- DRUG Aspirin
- DRUG Clopidogrel
- DRUG BMS-986177
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 2,366 participants |
| Start Date | 2019-01-27 |
| Est. Completion | 2022-03-31 |
| Phase | Phase 2 |
What the finished NCT03766581 record still lists
NCT03766581 is an interventional study that assigns participants to a tested intervention. Its 2,366 participants enrollment target places it among the larger protocols in the corpus, above the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (1679% higher).
The record links to 0 conditions, and to 4 interventions - of which Placebo is the first listed.
NCT03766581 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT03766581 about?
NCT03766581 is a clinical study titled "A Study on BMS-986177 for the Prevention of a Stroke in Patients Receiving Aspirin and Clopidogrel". The purpose of this clinical study is to determine whether the addition of an oral Factor XIa Inhibitor to Aspirin and Clopidogrel is more effective than standard therapy in secondary stroke prevention.
What is the current status of trial NCT03766581?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 2,366 participants. The study started on 2019-01-27. Estimated completion is 2022-03-31.
What interventions are being tested in trial NCT03766581?
The interventions under investigation include: Placebo (OTHER), Aspirin (DRUG), Clopidogrel (DRUG), BMS-986177 (DRUG).
Who is sponsoring clinical trial NCT03766581?
This trial is sponsored by Bristol-Myers Squibb, which has 1,025 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT03766581's enrollment target sits among peer trials
2,366 8th of 2000 higher than 1,993 of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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