Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

RECRUITING Phase 1

Phase 1/2 Study of Linvoseltamab in Adult Patients With Relapsed or Refractory Multiple Myeloma

NCT03761108 · View on ClinicalTrials.gov ↗

Study Summary

The main purpose of this study is to learn about the safety of linvoseltamab and to find out what is the best dose of linvoseltamab to give to patients with multiple myeloma and to look for any signs that linvoseltamab can effectively treat cancer. The study is looking at several other research questions, including: * Side effects that may be experienced by people receiving linvoseltamab * How linvoseltamab works in the body * How much linvoseltamab is present in the blood * How linvoseltamab may work to treat cancer

Conditions Studied

Interventions

  • DRUG Linvoseltamab

Study Locations (20)

Other

  • ZNA Psychiatrisch Ziekenhuis Stuivenberg — Antwerp
  • Cliniques Universitaires Saint-Luc — Brussels
  • Universitatsklinikum Wurzburg — Würzburg

Florida

  • Sylvester Comprehensive Cancer Center — Miami
  • Moffitt Cancer Center - McKinley Drive — Tampa

Michigan

  • C. S. Mott_University of Michigan — Ann Arbor
  • Barbara Ann Karmanos Cancer Center — Detroit

New York

  • Icahn School of Medicine at Mount Sinai — New York
  • Columbia University Medical Center — New York

Georgia

  • Emory University Hospital — Atlanta

Indiana

  • Indiana University_Michigan Street — Indianapolis

Kentucky

  • Norton Cancer Institute — Louisville

New Jersey

  • Rutgers Cancer Institute of New Jersey — New Brunswick

Trial Details

FieldValue
Enrollment Target 387 participants
Start Date 2019-01-23
Est. Completion 2033-06-16
Phase Phase 1

Sponsor

Regeneron Pharmaceuticals

290 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT03761108

The ClinicalTrials.gov registry entry for NCT03761108 describes a study currently listed as recruiting. It is categorized as Phase 1, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 387 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Regeneron Pharmaceuticals, which has 290 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 1 condition, with Multiple Myeloma appearing as the primary indexed condition, and to 1 intervention — of which Linvoseltamab is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT03761108 reports 20 study locations spanning 15 distinct geographic areas — top geographies include Other, Florida, Michigan. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT03761108 about?

NCT03761108 is a clinical study titled "Phase 1/2 Study of Linvoseltamab in Adult Patients With Relapsed or Refractory Multiple Myeloma". The main purpose of this study is to learn about the safety of linvoseltamab and to find out what is the best dose of linvoseltamab to give to patients with multiple myeloma and to look for any signs that linvoseltamab can effectively treat cancer. The study is looking at several other research que...

What is the current status of trial NCT03761108?

This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 387 participants. The study started on 2019-01-23. Estimated completion is 2033-06-16.

What conditions does trial NCT03761108 study?

This clinical trial studies the following conditions: Multiple Myeloma. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT03761108?

The interventions under investigation include: Linvoseltamab (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT03761108?

This trial is sponsored by Regeneron Pharmaceuticals, which has 290 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT03761108 being conducted?

This trial has 20 study locations across Florida, Georgia, Indiana, Kentucky, Michigan. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial