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NCT03760718 · ClinicalTrials.gov registry record · Early Phase 1
Chloroprocaine Lavage to Improve Outcomes Related to Operative Cesarean Delivery
A Early Phase 1 study, sponsored by Oregon Health and Science University.
- Completed
- Registry status
- Early Phase 1
- Development phase
- 15
- Enrollment target
NCT03760718: Completed Early Phase 1 study, sponsored by Oregon Health and Science University.
NCT03760718 is a Early Phase 1 study that has completed, run by Oregon Health and Science University. The registered enrollment target is 15 participants, below the 53-participant average among 2,764 other Early Phase 1 trials with a reported enrollment target (72% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03760718, a Early Phase 1 study, has completed, sponsored by Oregon Health and Science University.
- COMPLETED
- Registry status
- Early Phase 1
- Development phase
- 15 participants
- Enrollment target
Study Summary
The long term objective is to show that intraperitoneal chloroprocaine can be used an alternative option to avoid general anesthesia during cesarean delivery, to alleviate mother's discomfort from surgical pain, reduce complications, and improve the birth experience. The objectives in this study are to determine the amount of chloroprocaine that is absorbed into the blood in order to create a plasma concentration time profile and to determine the incidence of side effects to help guide selection of an appropriate concentration for future study.
Primary Outcome
The chloroprocaine plasma concentration obtained from a venous sample 1 minute after intraperitoneal chloroprocaine administration.
Interventions
- DRUG Preservative free 1% Chloroprocaine
- DRUG Preservative free 2% Chloroprocaine
- DRUG Preservative free 3% Chloroprocaine
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 15 participants |
| Start Date | 2019-09-30 |
| Est. Completion | 2021-12-31 |
| Phase | Early Phase 1 |
What the finished NCT03760718 record still lists
NCT03760718 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 15 participants, a relatively small participant target, below the 53-participant average among 2,764 other Early Phase 1 trials with a reported enrollment target (72% lower).
The record links to 0 conditions, and to 3 interventions - of which Preservative free 1% Chloroprocaine is the first listed.
NCT03760718 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT03760718 about?
NCT03760718 is a clinical study titled "Chloroprocaine Lavage to Improve Outcomes Related to Operative Cesarean Delivery". The long term objective is to show that intraperitoneal chloroprocaine can be used an alternative option to avoid general anesthesia during cesarean delivery, to alleviate mother's discomfort from surgical pain, reduce complications, and improve the birth experience. The objectives in this study are...
What is the current status of trial NCT03760718?
This trial is currently completed. It is a Early Phase 1 study. The enrollment target is 15 participants. The study started on 2019-09-30. Estimated completion is 2021-12-31.
What interventions are being tested in trial NCT03760718?
The interventions under investigation include: Preservative free 1% Chloroprocaine (DRUG), Preservative free 2% Chloroprocaine (DRUG), Preservative free 3% Chloroprocaine (DRUG).
Who is sponsoring clinical trial NCT03760718?
This trial is sponsored by Oregon Health and Science University, which has 546 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT03760718's enrollment target sits among peer trials
15 1403rd of 2000 higher than 527 of 2,000 other Early Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Early Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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