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NCT03757910 · ClinicalTrials.gov registry record · Early Phase 1
Brain Imaging in the Diabetes Prevention Program Outcomes Study
A Early Phase 1 study, sponsored by José A. Luchsinger.
- Terminated
- Registry status
- Early Phase 1
- Development phase
- 5
- Enrollment target
NCT03757910: Clinical Trial Early Phase 1 study, sponsored by José A. Luchsinger.
NCT03757910 is a Early Phase 1 study that was terminated before completion, run by José A. Luchsinger. The registered enrollment target is 5 participants, below the 53-participant average among 2,764 other Early Phase 1 trials with a reported enrollment target (91% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03757910, a Early Phase 1 study, was terminated before completion, sponsored by José A. Luchsinger.
- TERMINATED
- Registry status
- Early Phase 1
- Development phase
- 5 participants
- Enrollment target
Study Summary
This is a cross-sectional pilot study of Alzheimer's disease (AD) brain imaging biomarkers in Diabetes Prevention Program (DPP) outcomes study (DPPOS) participants from the New York City sites (Columbia and Einstein), comparing 10 persons originally randomized to metformin and 10 persons randomized to placebo in DPP. All study procedures will be conducted at Columbia University Irving Medical Center. Eligible participants will receive a PET scans and a brain MRI, which may be conducted in one, two, or three separate visits.
Primary Outcome
Whole brain amyloid (11C-PIB) standardized uptake volume ratio (SUVR)
Interventions
- DRUG 18F-MK-6240
- DRUG 11C-PIB
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 5 participants |
| Start Date | 2019-10-01 |
| Est. Completion | 2023-01-31 |
| Phase | Early Phase 1 |
Why NCT03757910 stopped before completion
NCT03757910 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 5 participants, a relatively small participant target, below the 53-participant average among 2,764 other Early Phase 1 trials with a reported enrollment target (91% lower).
The record links to 0 conditions, and to 2 interventions - of which 18F-MK-6240 is the first listed.
NCT03757910 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT03757910 about?
NCT03757910 is a clinical study titled "Brain Imaging in the Diabetes Prevention Program Outcomes Study". This is a cross-sectional pilot study of Alzheimer's disease (AD) brain imaging biomarkers in Diabetes Prevention Program (DPP) outcomes study (DPPOS) participants from the New York City sites (Columbia and Einstein), comparing 10 persons originally randomized to metformin and 10 persons randomized ...
What is the current status of trial NCT03757910?
This trial is currently terminated. It is a Early Phase 1 study. The enrollment target is 5 participants. The study started on 2019-10-01. Estimated completion is 2023-01-31.
What interventions are being tested in trial NCT03757910?
The interventions under investigation include: 18F-MK-6240 (DRUG), 11C-PIB (DRUG).
Who is sponsoring clinical trial NCT03757910?
This trial is sponsored by José A. Luchsinger, which has 2 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT03757910's enrollment target sits among peer trials
5 1887th of 2000 higher than 80 of 2,000 other Early Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Early Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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