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NCT03757325 · ClinicalTrials.gov registry record · Phase 1

Study to Evaluate DNL747 in Subjects With Alzheimer's Disease

A Phase 1 study, sponsored by Denali Therapeutics.

Completed
Registry status
Phase 1
Development phase
16
Enrollment target

NCT03757325 is a Phase 1 study that has completed, run by Denali Therapeutics. The registered enrollment target is 16 participants.

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The verdict

NCT03757325, a Phase 1 study, has completed, sponsored by Denali Therapeutics.

COMPLETED
Registry status
Phase 1
Development phase
16 participants
Enrollment target

Study Summary

The purpose of this study is to evaluate the safety, tolerability, pharmacokinetics, and pharmacodynamics of multiple oral doses of DNL747 in subjects with Alzheimer's disease when administered for 29 days in a cross-over design

Interventions

  • DRUG Placebo
  • DRUG DNL747

Trial Details

FieldValue
Enrollment Target 16 participants
Start Date 2019-02-13
Est. Completion 2019-12-05
Phase Phase 1

Sponsor

Denali Therapeutics

12 total trials

What the Registry Record Tells You About NCT03757325

The ClinicalTrials.gov registry entry for NCT03757325 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 16 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Denali Therapeutics, which has 12 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 2 interventions - of which Placebo is the first listed.

NCT03757325 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT03757325 about?

NCT03757325 is a clinical study titled "Study to Evaluate DNL747 in Subjects With Alzheimer's Disease". The purpose of this study is to evaluate the safety, tolerability, pharmacokinetics, and pharmacodynamics of multiple oral doses of DNL747 in subjects with Alzheimer's disease when administered for 29 days in a cross-over design

What is the current status of trial NCT03757325?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 16 participants. The study started on 2019-02-13. Estimated completion is 2019-12-05.

What interventions are being tested in trial NCT03757325?

The interventions under investigation include: Placebo (DRUG), DNL747 (DRUG).

Who is sponsoring clinical trial NCT03757325?

This trial is sponsored by Denali Therapeutics, which has 12 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.