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NCT03755362 · ClinicalTrials.gov registry record · NA
Dental Carotid Cognitive Study
A NA study, sponsored by University of Maryland, Baltimore.
- Terminated
- Registry status
- NA
- Development phase
- 26
- Enrollment target
NCT03755362 is a NA study that was terminated before completion, run by University of Maryland, Baltimore. The registered enrollment target is 26 participants.
The verdict
NCT03755362, a NA study, was terminated before completion, sponsored by University of Maryland, Baltimore.
- TERMINATED
- Registry status
- NA
- Development phase
- 26 participants
- Enrollment target
Study Summary
Periodontal Disease (PD) is present in 60+% of adults \>65 years and is associated with tobacco smoking, diabetes, and atherosclerosis that worsen inflammation, comorbidities common in older people with mild to moderate cognitive impairment (MCI). Older MCI patients are prone to poor oral hygiene and dental health, which if untreated worsens inflammation-mediated brain and nervous system function, and accelerates progression to dementia. Asymptomatic carotid artery stenosis (ACAS) is often a silent disease detected in only \~10% of older adults, and may have a strong association with MCI. This study examines the effects of intensive therapy for periodontitis on cognition in high-risk older people with ACAS. Results could highlight PD as a readily modifiable risk factor for dementia.
Interventions
- PROCEDURE Standard Treatment
- PROCEDURE Intensive Treatment
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 26 participants |
| Start Date | 2019-04-08 |
| Est. Completion | 2021-02-25 |
| Phase | NA |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT03755362
The ClinicalTrials.gov registry entry for NCT03755362 describes a study currently listed as terminated, categorized as NA. The registered enrollment target is 26 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of Maryland, Baltimore, which has 560 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 2 interventions - of which Standard Treatment is the first listed.
NCT03755362 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT03755362 about?
NCT03755362 is a clinical study titled "Dental Carotid Cognitive Study". Periodontal Disease (PD) is present in 60+% of adults \>65 years and is associated with tobacco smoking, diabetes, and atherosclerosis that worsen inflammation, comorbidities common in older people with mild to moderate cognitive impairment (MCI). Older MCI patients are prone to poor oral hygiene an...
What is the current status of trial NCT03755362?
This trial is currently terminated. It is a NA study. The enrollment target is 26 participants. The study started on 2019-04-08. Estimated completion is 2021-02-25.
What interventions are being tested in trial NCT03755362?
The interventions under investigation include: Standard Treatment (PROCEDURE), Intensive Treatment (PROCEDURE).
Who is sponsoring clinical trial NCT03755362?
This trial is sponsored by University of Maryland, Baltimore, which has 560 total clinical trials registered on ClinicalTrials.gov.
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