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NCT03748992 · ClinicalTrials.gov registry record · Phase 2
A Proof of Concept Study of Inhaled Nitric Oxide for Adults With Pulmonary Non-Tuberculous Mycobacterial Infection
A Phase 2 study, sponsored by Medical University of South Carolina.
- Completed
- Registry status
- Phase 2
- Development phase
- 10
- Enrollment target
NCT03748992: Completed Phase 2 study, sponsored by Medical University of South Carolina.
NCT03748992 is a Phase 2 study that has completed, run by Medical University of South Carolina. The registered enrollment target is 10 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (92% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03748992, a Phase 2 study, has completed, sponsored by Medical University of South Carolina.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 10 participants
- Enrollment target
Study Summary
The purpose of this study is to evaluate the efficacy and safety of open-label exposure of gNO in patients with NTM lung disease. Subjects will receive the study drug by inhaling through a nasal mask. Subjects will be treated for 3 weeks (5 days per week) and followed monthly for 3 months.
Primary Outcome
Sputum culture will be assessed for any sputum growth. A negative culture represents no mycobacterial growth.
Interventions
- DRUG gNO
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 10 participants |
| Start Date | 2019-01-28 |
| Est. Completion | 2020-03-26 |
| Phase | Phase 2 |
What the finished NCT03748992 record still lists
NCT03748992 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 10 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (92% lower).
The record links to 0 conditions, and to 1 intervention - of which gNO is the first listed.
NCT03748992 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT03748992 about?
NCT03748992 is a clinical study titled "A Proof of Concept Study of Inhaled Nitric Oxide for Adults With Pulmonary Non-Tuberculous Mycobacterial Infection". The purpose of this study is to evaluate the efficacy and safety of open-label exposure of gNO in patients with NTM lung disease. Subjects will receive the study drug by inhaling through a nasal mask. Subjects will be treated for 3 weeks (5 days per week) and followed monthly for 3 months.
What is the current status of trial NCT03748992?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 10 participants. The study started on 2019-01-28. Estimated completion is 2020-03-26.
What interventions are being tested in trial NCT03748992?
The interventions under investigation include: gNO (DRUG).
Who is sponsoring clinical trial NCT03748992?
This trial is sponsored by Medical University of South Carolina, which has 755 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT03748992's enrollment target sits among peer trials
10 1968th of 2000 higher than 12 of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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