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NCT03748173 · ClinicalTrials.gov registry record · Phase 1

Infasurf®(Calfactant) Aerosol for Infants With Bronchiolitis-AERO-04

A Phase 1 study, sponsored by ONY.

Terminated
Registry status
Phase 1
Development phase
13
Enrollment target

NCT03748173: Clinical Trial Phase 1 study, sponsored by ONY.

NCT03748173 is a Phase 1 study that was terminated before completion, run by ONY. The registered enrollment target is 13 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (78% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT03748173, a Phase 1 study, was terminated before completion, sponsored by ONY.

TERMINATED
Registry status
Phase 1
Development phase
13 participants
Enrollment target

Study Summary

Delivery of aerosolized Infasurf to bronchiolitis patients with who are not on assisted ventilation can provide sufficient delivery of Infasurf to small airways to improve ventilation and thereby shorten the duration of the respiratory illness.

Primary Outcome

Incidence of positive respiratory response to Infasurf® Aerosol defined as Bronchiolitis Clinical Score decreased by 2 points or to ≤4.

Interventions

  • COMBINATION_PRODUCT Aerosolized Infasurf

Trial Details

FieldValue
Enrollment Target 13 participants
Start Date 2019-01-12
Est. Completion 2020-10-21
Phase Phase 1
ONY

3 total trials

Why NCT03748173 stopped before completion

NCT03748173 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 13 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (78% lower).

The record links to 0 conditions, and to 1 intervention - of which Aerosolized Infasurf is the first listed.

NCT03748173 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT03748173 about?

NCT03748173 is a clinical study titled "Infasurf®(Calfactant) Aerosol for Infants With Bronchiolitis-AERO-04". Delivery of aerosolized Infasurf to bronchiolitis patients with who are not on assisted ventilation can provide sufficient delivery of Infasurf to small airways to improve ventilation and thereby shorten the duration of the respiratory illness.

What is the current status of trial NCT03748173?

This trial is currently terminated. It is a Phase 1 study. The enrollment target is 13 participants. The study started on 2019-01-12. Estimated completion is 2020-10-21.

What interventions are being tested in trial NCT03748173?

The interventions under investigation include: Aerosolized Infasurf (COMBINATION_PRODUCT).

Who is sponsoring clinical trial NCT03748173?

This trial is sponsored by ONY, which has 3 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT03748173's enrollment target sits among peer trials

13 1847th of 2000 higher than 149 of 2,000 other Phase 1 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT03748173, the US trial registry maintained by the National Library of Medicine. NCT03748173 (small enrollment · none site footprint · terminated) retrieved and formatted by PlainTrial, see methodology.