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NCT03739645 · ClinicalTrials.gov registry record · NA
Human Behaviors Related to the Expectation of Pain
A NA study, sponsored by Johns Hopkins University.
- Terminated
- Registry status
- NA
- Development phase
- 32
- Enrollment target
NCT03739645: Clinical Trial NA study, sponsored by Johns Hopkins University.
NCT03739645 is a NA study that was terminated before completion, run by Johns Hopkins University. The registered enrollment target is 32 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (98% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03739645, a NA study, was terminated before completion, sponsored by Johns Hopkins University.
- TERMINATED
- Registry status
- NA
- Development phase
- 32 participants
- Enrollment target
Study Summary
The conditioned expectation of pain is an important aspect of pain-related disability produced by environments and stimuli associated with a painful injury on the job, although the neuroscience of this expectation is unclear. We will develop and use novel objective methods for measurement of expectation and threat related attention. The results of this study may lead to testable hypotheses regarding the psychological basis of the fear of pain, threat and task related attention. We will also use these results, and development of novel autonomic and ratings metrics for state and trait anxiety as well as threat and task related attention which could be used as an instrumented test for diagnosis and management of PTSD and anxiety disorders. .
Primary Outcome
Concrete metric is skin conductance response to painful laser pulse stimulus measured in microSiemens. Higher values mean more emotional arousal or stress. All participants experienced two types of conditioned stimuli, one stimulus signaled danger and the other safety. Only during the danger stimulus would the participant receive a laser pulse.
Interventions
- BEHAVIORAL Skin conductance levels and slopes over time in conditioned fear as metrics.as metrics for anxiety
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 32 participants |
| Start Date | 2020-08-01 |
| Est. Completion | 2023-10-01 |
| Phase | NA |
Why NCT03739645 stopped before completion
NCT03739645 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 32 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (98% lower).
The record links to 0 conditions, and to 1 intervention - of which Skin conductance levels and slopes over time in conditioned fear as metrics.as metrics for anxiety is the first listed.
NCT03739645 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT03739645 about?
NCT03739645 is a clinical study titled "Human Behaviors Related to the Expectation of Pain". The conditioned expectation of pain is an important aspect of pain-related disability produced by environments and stimuli associated with a painful injury on the job, although the neuroscience of this expectation is unclear. We will develop and use novel objective methods for measurement of expecta...
What is the current status of trial NCT03739645?
This trial is currently terminated. It is a NA study. The enrollment target is 32 participants. The study started on 2020-08-01. Estimated completion is 2023-10-01.
What interventions are being tested in trial NCT03739645?
The interventions under investigation include: Skin conductance levels and slopes over time in conditioned fear as metrics.as metrics for anxiety (BEHAVIORAL).
Who is sponsoring clinical trial NCT03739645?
This trial is sponsored by Johns Hopkins University, which has 1,448 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT03739645's enrollment target sits among peer trials
32 1578th of 2000 higher than 409 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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