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NCT03736343 · ClinicalTrials.gov registry record · Early Phase 1
Impulsivity and Alcohol Response
A Early Phase 1 study, sponsored by University of Florida.
- Terminated
- Registry status
- Early Phase 1
- Development phase
- 24
- Enrollment target
NCT03736343 is a Early Phase 1 study that was terminated before completion, run by University of Florida. The registered enrollment target is 24 participants.
The verdict
NCT03736343, a Early Phase 1 study, was terminated before completion, sponsored by University of Florida.
- TERMINATED
- Registry status
- Early Phase 1
- Development phase
- 24 participants
- Enrollment target
Study Summary
Impulsivity, a well-known risk factor predicting negative outcomes, refers broadly to a proclivity towards rapid action with a suboptimal regard for future consequences. Importantly, impulsivity is a multidimensional construct incorporating generalized and behavioral facets. However, underlying mechanisms linking facets of impulsivity to high-risk drinking remain uncertain. Such mechanisms, if uncovered, may be more appropriate intervention targets than impulsivity directly. Similar to impulsivity, subjective response to alcohol (SR), or individual differences in sensitivity to the pharmacologic effects of alcohol, is an established risk factor for alcohol use disorder. Specifically, experiencing heightened rewarding stimulation and dampened aversive sedation from alcohol are related to high-risk drinking. Theory and recent findings indicate SR and impulsivity may be related, suggesting SR may be a mechanism linking facets of impulsivity to high-risk drinking. However, findings linking impulsivity to SR were all from secondary data analyses and most studies reported on only a single measure of impulsivity. For these reasons, an original data collection using laboratory alcohol administration methods is needed to address which facets of impulsivity are related to SR among young adult drinkers and whether these effects manifest while blood alcohol concentrations are increasing or declining. This study will utilize a laboratory alcohol administration design to investigate whether distinct facets of impulsivity (i.e., generalized, choice, response) are related to subjective responses (i.e., stimulation and sedation) following alcohol administration.
Interventions
- DRUG Alcohol
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 24 participants |
| Start Date | 2019-05-01 |
| Est. Completion | 2022-10-17 |
| Phase | Early Phase 1 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT03736343
The ClinicalTrials.gov registry entry for NCT03736343 describes a study currently listed as terminated, categorized as Early Phase 1. The registered enrollment target is 24 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of Florida, which has 1,106 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 1 intervention - of which Alcohol is the first listed.
NCT03736343 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT03736343 about?
NCT03736343 is a clinical study titled "Impulsivity and Alcohol Response". Impulsivity, a well-known risk factor predicting negative outcomes, refers broadly to a proclivity towards rapid action with a suboptimal regard for future consequences. Importantly, impulsivity is a multidimensional construct incorporating generalized and behavioral facets. However, underlying mech...
What is the current status of trial NCT03736343?
This trial is currently terminated. It is a Early Phase 1 study. The enrollment target is 24 participants. The study started on 2019-05-01. Estimated completion is 2022-10-17.
What interventions are being tested in trial NCT03736343?
The interventions under investigation include: Alcohol (DRUG).
Who is sponsoring clinical trial NCT03736343?
This trial is sponsored by University of Florida, which has 1,106 total clinical trials registered on ClinicalTrials.gov.
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