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NCT03731364 · ClinicalTrials.gov registry record · Phase 2
Study of CA-008 (Vocacapsaicin) in Total Knee Arthroplasty
A Phase 2 study, sponsored by Concentric Analgesics.
- Completed
- Registry status
- Phase 2
- Development phase
- 55
- Enrollment target
NCT03731364: Completed Phase 2 study, sponsored by Concentric Analgesics.
NCT03731364 is a Phase 2 study that has completed, run by Concentric Analgesics. The registered enrollment target is 55 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (59% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03731364, a Phase 2 study, has completed, sponsored by Concentric Analgesics.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 55 participants
- Enrollment target
Study Summary
This is a two-part, Phase 2, multi-center, randomized, double-blind, placebo-controlled, parallel design study of CA-008 (vocacapsaicin) vs. placebo injected/instilled during an elective TKA.
Primary Outcome
Primary Efficacy Endpoint for the Pilot Stage. Time-specific mean pain intensity scores at Time 96 hours for CA-008 vs. placebo based on a 10-point numerical rating scale (NRS) from 0-10 where 0 is no pain and 10 is the worst pain imaginable).
Interventions
- DRUG Placebo
- DRUG CA-008
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 55 participants |
| Start Date | 2018-10-29 |
| Est. Completion | 2019-05-31 |
| Phase | Phase 2 |
What the finished NCT03731364 record still lists
NCT03731364 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 55 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (59% lower).
The record links to 0 conditions, and to 2 interventions - of which Placebo is the first listed.
NCT03731364 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT03731364 about?
NCT03731364 is a clinical study titled "Study of CA-008 (Vocacapsaicin) in Total Knee Arthroplasty". This is a two-part, Phase 2, multi-center, randomized, double-blind, placebo-controlled, parallel design study of CA-008 (vocacapsaicin) vs. placebo injected/instilled during an elective TKA.
What is the current status of trial NCT03731364?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 55 participants. The study started on 2018-10-29. Estimated completion is 2019-05-31.
What interventions are being tested in trial NCT03731364?
The interventions under investigation include: Placebo (DRUG), CA-008 (DRUG).
Who is sponsoring clinical trial NCT03731364?
This trial is sponsored by Concentric Analgesics, which has 7 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT03731364's enrollment target sits among peer trials
55 1153rd of 2000 higher than 841 of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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