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NCT03731052 · ClinicalTrials.gov registry record · Phase 3
Comparison of 188-0551 Spray Versus Vehicle Spray in Subjects With Plaque Psoriasis (307)
A Phase 3 study, sponsored by Therapeutics.
- Completed
- Registry status
- Phase 3
- Development phase
- 217
- Enrollment target
NCT03731052: Completed Phase 3 study, sponsored by Therapeutics.
NCT03731052 is a Phase 3 study that has completed, run by Therapeutics. The registered enrollment target is 217 participants, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (72% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03731052, a Phase 3 study, has completed, sponsored by Therapeutics.
- COMPLETED
- Registry status
- Phase 3
- Development phase
- 217 participants
- Enrollment target
Study Summary
This Phase 3 study (Study 307) has been designed to determine and compare the efficacy and safety of 188-0551 Spray and Vehicle Spray applied twice daily for up to four weeks in subjects with plaque psoriasis. Subjects will be instructed to apply the test article (188-0551 Spray or Vehicle Spray) to all psoriasis plaques within the designated Treatment Area twice daily for four weeks (Study Day 29), unless the investigator verifies the subject's psoriasis has cleared at Day 15, then test article application will be for 2 weeks (Study Day 15).
Primary Outcome
The primary efficacy endpoint will be the percentage of subjects with IGA treatment success at End of Study (EOS) where EOS is the subject's last completed post-Baseline visit (Day 29).
Interventions
- DRUG Vehicle Spray
- DRUG 188-0551 Spray
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 217 participants |
| Start Date | 2018-10-16 |
| Est. Completion | 2019-12-20 |
| Phase | Phase 3 |
What the finished NCT03731052 record still lists
NCT03731052 is an interventional study that assigns participants to a tested intervention. The registered 217 participants enrollment target is mid-sized for trials with a published cap, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (72% lower).
The record links to 0 conditions, and to 2 interventions - of which Vehicle Spray is the first listed.
NCT03731052 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT03731052 about?
NCT03731052 is a clinical study titled "Comparison of 188-0551 Spray Versus Vehicle Spray in Subjects With Plaque Psoriasis (307)". This Phase 3 study (Study 307) has been designed to determine and compare the efficacy and safety of 188-0551 Spray and Vehicle Spray applied twice daily for up to four weeks in subjects with plaque psoriasis. Subjects will be instructed to apply the test article (188-0551 Spray or Vehicle Spray) to...
What is the current status of trial NCT03731052?
This trial is currently completed. It is a Phase 3 study. The enrollment target is 217 participants. The study started on 2018-10-16. Estimated completion is 2019-12-20.
What interventions are being tested in trial NCT03731052?
The interventions under investigation include: Vehicle Spray (DRUG), 188-0551 Spray (DRUG).
Who is sponsoring clinical trial NCT03731052?
This trial is sponsored by Therapeutics, which has 17 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT03731052's enrollment target sits among peer trials
217 1332nd of 2000 higher than 669 of 2,000 other Phase 3 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 3 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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