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NCT03724032 · ClinicalTrials.gov registry record · NA
Investigation and Modulation of the Mu-opioid Mechanisms in TMD (in Vivo)
A NA study, sponsored by University of Michigan.
- Terminated
- Registry status
- NA
- Development phase
- 15
- Enrollment target
NCT03724032: Clinical Trial NA study, sponsored by University of Michigan.
NCT03724032 is a NA study that was terminated before completion, run by University of Michigan. The registered enrollment target is 15 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03724032, a NA study, was terminated before completion, sponsored by University of Michigan.
- TERMINATED
- Registry status
- NA
- Development phase
- 15 participants
- Enrollment target
Study Summary
In this study, this team of researchers will investigate the impact of chronic temporomandibular disorder suffering on the endogenous μ-opioid system in vivo, arguably one of the principal endogenous pain modulatory systems in the brain, and its modulation by 10 daily sessions of primary motor cortex stimulation using high-definition transcranial direct current stimulation (HD-tDCS).
Primary Outcome
Change in clinical Visual Analog Scale pain score from baseline (Screening Day) to 4 weeks after completion of HD-tDCS sessions (Follow Up #2). Pain is measured on a scale of 1-10, with 10 being the worst.
Interventions
- DEVICE HD-tDCS*
- DEVICE Sham HD-tDCS*
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 15 participants |
| Start Date | 2018-12-13 |
| Est. Completion | 2022-01-17 |
| Phase | NA |
Why NCT03724032 stopped before completion
NCT03724032 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 15 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower).
The record links to 0 conditions, and to 2 interventions - of which HD-tDCS* is the first listed.
NCT03724032 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT03724032 about?
NCT03724032 is a clinical study titled "Investigation and Modulation of the Mu-opioid Mechanisms in TMD (in Vivo)". In this study, this team of researchers will investigate the impact of chronic temporomandibular disorder suffering on the endogenous μ-opioid system in vivo, arguably one of the principal endogenous pain modulatory systems in the brain, and its modulation by 10 daily sessions of primary motor corte...
What is the current status of trial NCT03724032?
This trial is currently terminated. It is a NA study. The enrollment target is 15 participants. The study started on 2018-12-13. Estimated completion is 2022-01-17.
What interventions are being tested in trial NCT03724032?
The interventions under investigation include: HD-tDCS* (DEVICE), Sham HD-tDCS* (DEVICE).
Who is sponsoring clinical trial NCT03724032?
This trial is sponsored by University of Michigan, which has 1,327 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT03724032's enrollment target sits among peer trials
15 1881st of 2000 higher than 92 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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